Results 81 to 90 of about 3,749,228 (399)

Phosphoproteomic profiling of lipopolysaccharide stimulated toll-like receptor pathways in macrophages

Scientific Data
Toll-like receptors (TLRs) are present on the surface of immune cells such as dendritic cells, macrophages, and natural killer cells. TLRs and other pattern recognition receptors (PRRs) are essential for the recognition of microbiological components ...
Doeun Kim, Sung Hwan Yoon, Nathan P. Manes, Aleksandra Nita-Lazar   +3 more
doaj   +1 more source

PARP Inhibition Shifts Murine Myeloid Cells Toward a More Tolerogenic Profile In Vivo

Biomolecules
The human Poly ADP-ribose Polymerase (PARP) family comprises 17 enzymes responsible for the transfer of ADP-ribose to proteins, forming poly- or mono-ADP-ribosylation.
Jose R. Pittaluga-Villarreal, Casey M. Daniels, Tara Capece, Pauline R. Kaplan, Martin Meier-Schellersheim, Aleksandra Nita-Lazar   +5 more
doaj   +1 more source

A syndrome featuring developmental disorder of the nervous system induced by a novel mutation in the TCF20 gene, rarely concurrent immune disorders: a case report

Frontiers in Genetics, 2023
Background: The expression of TCF20 is the most widespread in brain tissue. TCF20 depletion or mutation can affect the proliferation and differentiation of embryonic neurons, leading to developmental disorder of the central nervous system and subsequent ...
Si Huang, Si Huang, Si Huang, Si Huang, Jiaxin Xu, Yiyang Li, Wenhui Mo, Xiuwen Lin, Yajun Wang, Yajun Wang, Yajun Wang, Fujian Liang, Yan Bai, Guochun Huang, Jing Chen, Jing Xin, Guoda Ma, Guoda Ma, Guoda Ma   +18 more
doaj   +1 more source

Immune cognition, social justice and asthma: structured stress and the developing immune system [PDF]

, 2001
We explore the implications of IR Cohen's work on immune cognition for understanding rising rates of asthma morbidity and mortality in the US. Immune cognition is conjoined with central nervous system cognition, and with the cognitive function of the ...
Fullilove, Mindy, Wallace, Deborah, Wallace, Rodrick   +2 more
core  

Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. [PDF]

, 2015
Vitamin A has biological functions as diverse as sensing light for vision, regulating stem cell differentiation, maintaining epithelial integrity, promoting immune competency, regulating learning and memory, and acting as a key developmental morphogen ...
Kassai, Miki, Kawaguchi, Riki, Sun, Hui, Ter-Stepanian, Mariam, Zhong, Ming   +4 more
core   +2 more sources

The interaction of innate immune and adaptive immune system

MedComm
The innate immune system serves as the body's first line of defense, utilizing pattern recognition receptors like Toll‐like receptors to detect pathogens and initiate rapid response mechanisms.
Ruyuan Wang, Caini Lan, K. Benlagha, Niels Olsen Saraiva Câmara, Heather Miller, Masato Kubo, Steffen Heegaard, Pamela Lee, Lu Yang, Huamei Forsman, Xingrui Li, Zhimin Zhai, Chaohong Liu   +12 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The Off-Label Use of Antineoplastics in Oncology Is Limited But Has Notable Scientific Support in a University Hospital Setting

Frontiers in Pharmacology, 2019
Purpose: The off-label (OL) use of antineoplastic drugs for the treatment of various types of tumors in patients of different disease stages is becoming a common occurrence.
Marta Herrero Fernandez, Raquel Molina Villaverde, Raquel Molina Villaverde, Raquel Molina Villaverde, Monica Arroyo Yustos, Monica Arroyo Yustos, Monica Arroyo Yustos, Fatima Navarro Expósito, Fatima Navarro Expósito, Fatima Navarro Expósito, Jose Luis Lopez Gonzalez, Jose Luis Lopez Gonzalez, Jose Luis Lopez Gonzalez, Maria Rosario Luque Infantes, Melchor Alvarez-Mon Soto, Melchor Alvarez-Mon Soto, Melchor Alvarez-Mon Soto   +16 more
doaj   +1 more source

Community Lynching and the US Asthma Epidemic [PDF]

, 2003
We explore the implications of IR Cohen's work on immune cognition for understanding rising rates of asthma morbidity and mortality in the US. Immune cognition is inherently linked with central nervous system cognition, and with the cognitive function ...
Fullilove, Mindy, Wallace, Deborah, Wallace, Rodrick   +2 more
core  

Infectious diseases and autoimmunity [PDF]

, 2011
Introduction: Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the ...
Deidda, Silvia, Delitala, Giuseppe, Delogu, Lucia Gemma, Manetti, Roberto   +3 more
core   +1 more source