Results 121 to 130 of about 1,940,460 (362)

Pathobiology of Secondary Immune Thrombocytopenia

Seminars in Hematology, 2009
Primary immune thrombocytopenic purpura (ITP) remains a diagnosis of exclusion both from nonimmune causes of thrombocytopenia and immune thrombocytopenia that develops in the context of other disorders (secondary immune thrombocytopenia). The pathobiology, natural history, and response to therapy of the diverse causes of secondary ITP differ from each ...
Douglas B. Cines, Howard A. Liebman, Roberto Stasi   +2 more
openaire   +2 more sources

First‐Line Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Retrospective, Multicenter, Real‐World Study

Head &Neck, EarlyView.
ABSTRACT Background In Europe, pembrolizumab with or without chemotherapy is the recommended first‐line treatment for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC), with a combined positive score (CPS) ≥ 1. In France, the TPExtreme (TPEx) regimen is preferred for CPS < 1.
Alizée Simon, Cyril Abdeddaim, DucTrung Nguyen, Patrice Gallet, Didier Peiffert, Aurélien Lambert, Lionnel Geoffrois   +6 more
wiley   +1 more source

Use of Romiplostim during pregnancy as a rescue therapy in primary immune thrombocytopenia: Literature review and case description

Platelets, 2020
Thrombocytopenia could appear during pregnancy, in up to 8–10% of the cases, where 3–5% is related to an autoimmune process so-called immune thrombocytopenia (ITP). We present a 34-year-old woman debuted at 13 weeks gestation, with a platelet count of 19 
Rodriguez Nuñez Rosa María, Rubio Lacambra Laura, Palomo Bravo Ángeles, Langenhorst Baniandres Laura   +3 more
doaj   +1 more source

Occult Hemorrhage in Immune Thrombocytopenia

Seminars in Hematology, 2013
Assessing clinical bleeding in patients with immune thrombocytopenia (ITP) and predicting future risk of major hemorrhage has proven to be a complicated task given the heterogeneity in bleeding manifestations. Although bleeding scales have been used for this purpose, they fail to account for occult or subclinical hemorrhage.
George R. Buchanan, Adolfo Flores
openaire   +3 more sources

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Immune thrombocytopenia in lymphoproliferative diseases [PDF]

, 1979
BR Kaden, WF Rosse, TW Hauch
openalex   +1 more source

Recent advances in the mechanisms and treatment of immune thrombocytopenia

EBioMedicine, 2022
D. Provan, J. Semple
semanticscholar   +1 more source

Drug-Induced Immune Thrombocytopenia

Drug Safety, 2004
Thrombocytopenia can have several causes, including the use of certain drugs. The mechanism behind drug-induced thrombocytopenia is either a decrease in platelet production (bone marrow toxicity) or an increased destruction (immune-mediated thrombocytopenia).
Patricia M. L. A. van den Bemt, Antoine C. G. Egberts, Ronald H. B. Meyboom, Ronald H. B. Meyboom   +3 more
openaire   +4 more sources

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

International Journal of Cancer, EarlyView.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea, Pierre Loap, Sofiane Allali, Alain Fourquet, Kim Cao, Youlia Kirova   +5 more
wiley   +1 more source

Clinical and Laboratory Analysis of Children Who Follow Up with Thrombocytopenia: A Retrospective Study

Güncel Pediatri
Introduction: Platelets are cells that play an important role in the first phase of hemostasis, where the clot plug is formed. Disorders in the number or function of platelets can lead to bleeding.
Yasemin Denkboy Öngen, Birol Baytan
doaj   +1 more source