Results 11 to 20 of about 2,852,359 (355)
Tumor microenvironment-mediated immune tolerance in development and treatment of gastric cancer
Frontiers in Immunology, 2022 Tumor microenvironment is the general term for all non-cancer components and their metabolites in tumor tissue. These components include the extracellular matrix, fibroblasts, immune cells, and endothelial cells.
Yuanda Liu +4 more
semanticscholar +1 more source
Advancements in immune tolerance [PDF]
Advanced Drug Delivery Reviews, 2008 In recent years, considerable attention has been given to immune tolerance and its potential clinical applications for the treatment of cancers and autoimmune diseases, and the prevention of allo-graft rejection and graft-versus-host diseases. Advances in our understanding of the underlying mechanisms of establishment and maintenance of immune ...
Shu Hsia Chen +3 more
openaire +3 more sources
Frontiers in Immunology, 2022 Immunotherapy for food-allergic patients has been effective in inducing desensitization in some populations, but long-term tolerance has remained an elusive target.
Carolyn H. Baloh +4 more
doaj +1 more source
Ferroptosis: a double-edged sword mediating immune tolerance of cancer
Cell Death and Disease, 2022 The term ferroptosis was put forward in 2012 and has been researched exponentially over the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed cell death, which belongs to a type of necrosis and is distinguished from ...
Q. Dang +5 more
semanticscholar +1 more source
A Breakdown of Immune Tolerance in the Cerebellum [PDF]
Brain Sciences, 2022 Cerebellar dysfunction can be associated with ataxia, dysarthria, dysmetria, nystagmus and cognitive deficits. While cerebellar dysfunction can be caused by vascular, traumatic, metabolic, genetic, inflammatory, infectious, and neoplastic events, the cerebellum is also a frequent target of autoimmune attacks. The underlying cause for this vulnerability
Christiane S. Hampe, Hiroshi Mitoma
openaire +3 more sources
Oncoimmunology, 2022 The poor progress of immunotherapy on osteosarcoma patients requires deeper delineation of immune tolerance mechanisms in the osteosarcoma microenvironment and a new therapeutic strategy.
Jinti Lin +12 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 CD4+CD25+Foxp3+T cell population is heterogenous and contains three major sub-groups. First, thymus derived T regulatory cells (tTreg) that are naïve/resting. Second, activated/memory Treg that are produced by activation of tTreg by antigen and cytokines.
Bruce M. Hall +17 more
doaj +1 more source
The immune response to malaria in utero. [PDF]
, 2020 Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core +1 more source
Immune Tolerance and Transplantation [PDF]
Seminars in Oncology, 2012 Successful allogeneic hematopoietic stem cell transplantation (HSCT) and solid organ transplantation require development of a degree of immune tolerance against allogeneic antigens. T lymphocytes play a critical role in allograft rejection, graft failure, and graft-versus-host disease (GVHD).
Marcel R.M. van den Brink +1 more
openaire +3 more sources
Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin
Nature Communications, 2023 Psoriasis is a chronic, systemic inflammatory condition primarily affecting skin. While the role of the immune compartment (e.g., T cells) is well established, the changes in the skin compartment are more poorly understood.
Qian Xiao +12 more
doaj +1 more source