Results 11 to 20 of about 327,289 (308)

Immune tolerance

Zdravniški Vestnik, 2011
BACKGROUND Regulation of human immune system through mechanisms of immune tolerance is an exceptionally important part of the homeostasis that protects the integrity of our organism.
Matjaž Jeras, Urban Švajger
doaj   +5 more sources

From chaos to control: Nobel insights in regulatory T cells and immune tolerance. [PDF]

Pflugers Arch
Estrada Brull A, Joller N.
europepmc   +3 more sources

Immune Tolerance Regulation Is Critical to Immune Homeostasis [PDF]

Journal of Immunology Research
The body’s immune response plays a critical role in defending against external or foreign antigens while also preserving tolerance to self-antigens. This equilibrium, referred to as immune homeostasis, is paramount for overall health.
Lei Han, Tianxiang Wu, Qin Zhang, Anning Qi, Xiaohui Zhou   +4 more
doaj   +2 more sources

Liver-Mediated Adaptive Immune Tolerance [PDF]

Frontiers in Immunology, 2019
The liver is an immunologically tolerant organ that is uniquely equipped to limit hypersensitivity to food-derived antigens and bacterial products through the portal vein and can feasibly accept liver allografts.
Meijuan Zheng, Zhigang Tian, Zhigang Tian   +2 more
doaj   +3 more sources

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review). [PDF]

Oncol Lett
Guan Z, Han L, Chen B, Ma Y, Ni Q, Wang Z, Yang J, Liu Z.   +7 more
europepmc   +3 more sources

Sea squirts and immune tolerance [PDF]

Disease Models & Mechanisms, 2009
Transplantation specificity and protective immunity occur in both adaptive and innate branches of the vertebrate immune system. Understanding the mechanisms that underlie specificity and self-tolerance of immune function has major significance, from preventing a rejection reaction after transplantation to dissecting the causes of autoimmune disease ...
Anthony W. De Tomaso
openalex   +4 more sources

Approaches to Establishing Tolerance in Immune Mediated Diseases

Frontiers in Immunology, 2021
The development of rational approaches to restore immune tolerance requires an iterative approach that builds on past success and utilizes new mechanistic insights into immune-mediated pathologies. This article will review concepts that have evolved from
Michelle F. Huffaker, Srinath Sanda, Sindhu Chandran, Sharon A. Chung, E. William St. Clair, Gerald T. Nepom, Dawn E. Smilek   +6 more
doaj   +1 more source

Biomarkers and mechanisms of tolerance induction in food allergic patients drive new therapeutic approaches

Frontiers in Immunology, 2022
Immunotherapy for food-allergic patients has been effective in inducing desensitization in some populations, but long-term tolerance has remained an elusive target.
Carolyn H. Baloh, Carolyn H. Baloh, Michelle F. Huffaker, Tanya Laidlaw, Tanya Laidlaw   +4 more
doaj   +1 more source

Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin

Nature Communications, 2023
Psoriasis is a chronic, systemic inflammatory condition primarily affecting skin. While the role of the immune compartment (e.g., T cells) is well established, the changes in the skin compartment are more poorly understood.
Qian Xiao, Joseph Mears, Aparna Nathan, Kazuyoshi Ishigaki, Yuriy Baglaenko, Noha Lim, Laura A. Cooney, Kristina M. Harris, Mark S. Anderson, David A. Fox, Dawn E. Smilek, James G. Krueger, Soumya Raychaudhuri   +12 more
doaj   +1 more source

Interleukin-5 (IL-5) Therapy Prevents Allograft Rejection by Promoting CD4+CD25+ Ts2 Regulatory Cells That Are Antigen-Specific and Express IL-5 Receptor

Frontiers in Immunology, 2021
CD4+CD25+Foxp3+T cell population is heterogenous and contains three major sub-groups. First, thymus derived T regulatory cells (tTreg) that are naïve/resting. Second, activated/memory Treg that are produced by activation of tTreg by antigen and cytokines.
Bruce M. Hall, Bruce M. Hall, Rachael M. Hall, Rachael M. Hall, Giang T. Tran, Giang T. Tran, Catherine M. Robinson, Catherine M. Robinson, Paul L. Wilcox, Paul L. Wilcox, Prateek K. Rakesh, Prateek K. Rakesh, Chuanmin Wang, Alexandra F. Sharland, Nirupama D. Verma, Nirupama D. Verma, Suzanne J. Hodgkinson, Suzanne J. Hodgkinson   +17 more
doaj   +1 more source