Results 211 to 220 of about 327,289 (308)

Large deletions in the <i>F8</i> gene predict immune tolerance induction failure in people with severe hemophilia A. [PDF]

Res Pract Thromb Haemost
Oomen I, Abdi A, Broer L, Camelo RM, Callado FMRA, Carvalho LEM, Calcaterra IL, Carcao M, Castaman G, Eikenboom JCJ, Fischer K, Franco VKB, Geissler J, Kuijpers TW, Leebeek FWG, Lillicrap D, Lorenzato CS, Mancuso ME, Matino D, Di Minno MND, Mo A, Mohseny AB, Nagelkerke SQ, Oldenburg J, Rezende SM, Rivard GE, Rydz N, Schols SEM, Tanck MWT, Voorberg J, Fijnvandraat K, Gouw SC, International GO-ITI Steering Group.   +32 more
europepmc   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Thymic epithelial cells amplify epigenetic noise to promote immune tolerance. [PDF]

Nature
Gamble N, Caldwell JA, McKeever J, Kaiser C, Bradu A, Dooley PJ, Klemm S, Greenleaf WJ, Hibino N, Dinner AR, Koh AS.   +10 more
europepmc   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Assessment of the risk of discontinuation of tenofovir disoproxil fumarate after delivery and the benefit of continued treatment in patients with immune tolerance. [PDF]

Front Med (Lausanne)
Liang H, Liang H, Hu B, Huang L, Liang H, Su M, Wang R, Su T, Li Q, Feng Y, Jiang J.   +10 more
europepmc   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

The role of probiotics in promoting systemic immune tolerance in systemic lupus erythematosus. [PDF]

Gut Pathog
Mohamed AH, Shafie A, Al-Samawi RI, Jamali MC, Ashour AA, Felemban MF, Alqarni A, Ahmad I, Mansuri N, Ahmad F, Yousif AAM.   +10 more
europepmc   +1 more source

Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

Hong Yu, Hiroshi Nishio, Joseph Barbi, Marisa Mitchell-Flack, Paolo Vignali, Ying Zheng, Andriana Lebid, Kwang‐Yu Chang, Juan Fu, Makenzie Higgins, Ching‐Tai Huang, Xuehong Zhang, Zhiguang Li, Lee Blosser, Ada Tam, Charles G. Drake, Drew M. Pardoll   +16 more
openalex   +1 more source

Stable T cell–dendritic cell interactions precede the development of both tolerance and immunity in vivo

, 2005
Guy Shakhar, Randall L. Lindquist, Dimitris Skokos, Diana Dudziak, Julie H. Huang, Michel C. Nussenzweig, Michael L. Dustin   +6 more
openalex   +1 more source

Light‐Controlled Exposure of Cancer Cells to Reactive Oxygen Species Using Organic Semiconductor Thin Films

Advanced Materials Interfaces, EarlyView.
Spin‐coated films of the conjugated polymer F8T2 (poly (9,9‐dioctylfluorene‐alt‐bithiophene)) generate superoxide at the film‐medium interface, enabling precise delivery of reactive oxygen species (ROS) as visible‐light “ROS patches.” Coated surfaces drive rapid, localised cytotoxicity in MCF7 cancer monolayers under white light, providing a reagent ...
Joe Kaye, Niculina Miron, Benjamin Fortes Mayer, Yukai Shi, Boyuan Chen, Lewis Krzeczkowski, Robert J. E. Westbrook, Saif A. Haque, Ali Salehi‐Reyhani   +8 more
wiley   +1 more source