Results 41 to 50 of about 792,578 (312)
Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host [PDF]
The cellular adaptive immune response plays a key role in resolving influenza infection. Experiments where individuals are successively infected with different strains within a short timeframe provide insight into the underlying viral dynamics and the role of a cross-reactive immune response in resolving an acute infection.
arxiv +1 more source
The most commonly used techniques for the in vivo evaluation of the cellular immune response include intracutaneous testing with microbial recall antigens or sensitization with neoantigens.
Bogner, Johannes R.+4 more
core +1 more source
Background Tick-borne encephalitis virus (TBEV) is an important human pathogen that can cause the serious illness tick-borne encephalitis (TBE). Patients with clinical symptoms can suffer from severe meningoencephalitis with sequelae that include ...
Angela D. A. Cornelius+7 more
doaj +1 more source
Model-based cellular kinetic analysis of SARS-CoV-2 infection: different immune response modes and treatment strategies [PDF]
Increasing number in global COVID-19 cases demands for mathematical model to analyze the interaction between the virus dynamics and the response of innate and adaptive immunity. Here, based on the assumption of a weak and delayed response of the innate and adaptive immunity in SARS-CoV-2 infection, we constructed a mathematical model to describe the ...
arxiv
Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]
Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Huitema, Edgar+3 more
core +2 more sources
Hepatitis B: Model Systems and Therapeutic Approaches
Hepatitis B virus (HBV) infection is a major global health issue and ranks among the top causes of liver cirrhosis and hepatocellular carcinoma. Although current antiviral medications, including nucleot(s)ide analogs and interferons, could inhibit the ...
Xiaoxiao Yu+6 more
doaj +1 more source
Background: Acute kidney injury (AKI) is a frequent complication in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) and is associated with high rates of mortality. We aimed to estimate serum high mobility group protein 1
Yu Liu+14 more
doaj +1 more source
Immunization and Aging: a Learning Process in the Immune Network [PDF]
The immune system can be thought as a complex network of different interacting elements. A cellular automaton, defined in shape-space, was recently shown to exhibit self-regulation and complex behavior and is, therefore, a good candidate to model the immune system.
arxiv +1 more source
Modeling tumor disease and sepsis by networks of adaptively coupled phase oscillators [PDF]
In this study, we provide a dynamical systems perspective to the modelling of pathological states induced by tumors or infection. A unified disease model is established using the innate immune system as the reference point. We propose a two-layer network model for carcinogenesis and sepsis based upon the interaction of parenchymal cells and immune ...
arxiv
Modulation of plant autophagy during pathogen attack [PDF]
In plants, the highly conserved catabolic process of autophagy has long been known as a means of maintaining cellular homeostasis and coping with abiotic stress conditions. Accumulating evidence has linked autophagy to immunity against invading pathogens,
Bozkurt, Tolga O.+9 more
core +1 more source