Results 241 to 250 of about 524,193 (311)

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Host immune responses and immune evasion mechanisms in Trypanosoma cruzi: implications for the immunopathogenesis of Chagas disease. [PDF]

Rev Soc Bras Med Trop
Andrade CMP.
europepmc   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Strain-Dependent Protective Innate Immunity Against <i>Pneumocystis</i> Pneumonia in Mice. [PDF]

J Fungi (Basel)
Inzerillo PC, Gigliotti F, Wright TW.
europepmc   +1 more source

A Wireless, Passive Multimodal Wearable Sensor With Decoupled Sensing Capabilities

Advanced Materials, EarlyView.
A wireless passive multimodal electronic skin is presented for the simultaneous perception of pressure, humidity, and odor through a frequency‐divided LC resonator array. The decoupled sensing architecture suppresses cross‐interference and enables independent signal readout under superimposed stimuli while maintaining high stability.
Wenjiang Han, Heng Xiao, Tianshuang Wang, Xiaoran Ding, Liupeng Zhao, Seokjoo Cho, Peng Sun, Inkyu Park, Geyu Lu   +8 more
wiley   +1 more source

Novel Organelle-Based Intracellular Immunity with Mechanistic and Therapeutic Implications. [PDF]

Barrier Immun
Xu K, Hung SY, Saaoud F, Shao Y, Lu Y, Liu J, Yuan B, Xiang H, Wang H, Yang X.   +9 more
europepmc   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

Beta-Glucan modulates monocyte plasticity and differentiation capacity to mitigate DSS-induced colitis. [PDF]

Elife
Lv Y, Fan Y, Gao Q, Chen Q, Hu Y, Wang L, Shi H, Chen E, Xu Q, Cai Y, Fan Q, Li L, Du D, Ren J, Cheng SC, Xu H.   +15 more
europepmc   +1 more source

Multilayered Digital Microfluidic Chip for Cell‐Based Assays

Advanced Materials Interfaces, EarlyView.
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden, Oksana K. Savchak, Burcu Gumuscu   +2 more
wiley   +1 more source

Multidimensional regulatory mechanisms of chicken immunity: focus on viral infection, intestinal microbiota and heat stress. [PDF]

Front Vet Sci
Wang Y, Yang M, Zhao J, Wu H, Wang K, Sun D, Zhang R, Xu Z, Cao Z, Ge C, Jia J, Liu L, Jian Z, Dou T, Zi X.   +14 more
europepmc   +1 more source