Results 261 to 270 of about 521,465 (311)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Tumor immune microenvironment in non-small cell lung cancer progression. [PDF]

Front Immunol
Jiang J, Zhong M, Wang J, Zhang Z, Li W, Deng Z.   +5 more
europepmc   +1 more source

Transglutaminase 2 regulates innate immunity: mechanisms and therapeutic implications. [PDF]

Oncoimmunology
D'Eletto M, Occhigrossi L, Colasuonno F, Bellanca V, Di Sano F, Montesano C, Ciccosanti F, Shi Y, Piacentini M, Rossin F.   +9 more
europepmc   +1 more source

New Postbiotic Derived from Sequential Fermentation of Two <i>Lacticaseibacillus</i> Strains Exerts Beneficial Effects on Epithelial Gut Barrier and Innate Immunity in Human Enterocytes. [PDF]

Microorganisms
Oglio F, Cadavere A, De Aloe M, Lintura A, Michelini M, Luongo C, Coppola S, Agizza A, Caldaria E, Carucci L.   +9 more
europepmc   +1 more source

Immunosenescence in Older Patients with Psoriasis: Mechanistic Insights and Opportunities for Biologic Therapy. [PDF]

Psoriasis (Auckl)
Wang W, Zha S, Sun L, Zhou D.
europepmc   +1 more source

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host. [PDF]

Rev Med Virol
Cimini E, Tartaglia E, Cristofanelli F, Gili S, Maggi F.   +4 more
europepmc   +1 more source

Targeting macrophage-driven NK cell immunosuppression to improve cancer immunotherapy. [PDF]

J Immunother Cancer
Redavid AR, Cifaldi L, Bei R, De Billy E, Fruci D.   +4 more
europepmc   +1 more source

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Innate Immunity

Pediatric Clinics of North America, 2019
The innate immune response system forms an important line of defense by deploying a limited number of receptors specific for conserved microbial components. This deployment generates a rapid inflammatory response, while activating the adaptive immune system.
Bani Preet, Kaur, Elizabeth, Secord
openaire   +3 more sources

Innate immunity and HIV

AIDS, 2001
The effects of innate immunity during HIV infection have been extensively studied in three areas: NK and gamma/delta T cells; IPC; and the complement system. Many other areas of study of how innate immunity functions during HIV infection remain relatively unexplored.
F P, Siegal, G T, Spear
openaire   +2 more sources