Results 251 to 260 of about 1,027,521 (307)

Innate immunity: current understandings and future perspectives. [PDF]

Signal Transduct Target Ther
Zou C, Ma T, Li J, Zhou X.
europepmc   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Recent Advances in Lipid Nanoparticles for Cancer Vaccines: From Antigen Delivery to Personalized Immunotherapy. [PDF]

Int J Mol Sci
Rachamala HK, Angom RS, Marepally S.
europepmc   +1 more source

Editorial: Novel insights in insect immunity: regulators, signaling, and mechanisms. [PDF]

Front Immunol
Hu X, Strachecka A, Wang F, Zhou H, Zhang K, Eleftherianos I, Mohamed A.   +6 more
europepmc   +1 more source

Non-coding RNA-mediated tug-of-war between emerging viruses and host antiviral defense: lessons from animal viruses. [PDF]

Emerg Microbes Infect
Chen N, Zhang B, Yu Z, Tong G, Jin J, Jiang Q, Chen X.   +6 more
europepmc   +1 more source

From emergency myelopoiesis to trained immunity? Reframing post-stroke myeloid reprogramming along the brain-bone marrow axis. [PDF]

Front Neurol
Wei T, Wang Y.
europepmc   +1 more source

Cancer-associated fibroblasts and innate immune cells: orchestrators of the immunosuppressive tumor microenvironment. [PDF]

Front Immunol
Zinovkin DA, Korneva YS, Arafat HM, Shamallakh OM, Zinovkina ES, Davydov DA, Portyanko AS, Slepokurova II, Lyzikova YA, Pranjol MZI.   +9 more
europepmc   +1 more source

The Framework of Host Innate and Adaptive Immunological Pathways. [PDF]

Biomedicines
Hu WC.
europepmc   +1 more source