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Complement and innate immunity
Immunopharmacology, 2000Wen-Chao Song , Maria Rosa Sarrias , John D. Lambris b,) a Center for Experimental Therapeutics and Department of Pharmacology, UniOersity of PennsylOania School of Medicine, 1351 BRBIIr III, 421 Curie BlOd., Philadelphia, PA 19104, USA b Protein Chemistry Laboratory, Department of Pathology and Laboratory Medicine, UniOersity of PennsylOania School of
W C, Song, M R, Sarrias, J D, Lambris
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Immunology Letters, 2014
The innate immune response is of prime importance in the immediate recognition and elimination of invading micro-organisms. However, deregulation of this system is clearly associated with the pathogenesis of a wide range of inflammatory diseases. Innate immunity consists of a humoral and a cellular branch, which are closely interacting.
Koenderman, L., Buurman, W., Daha, M.R.
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The innate immune response is of prime importance in the immediate recognition and elimination of invading micro-organisms. However, deregulation of this system is clearly associated with the pathogenesis of a wide range of inflammatory diseases. Innate immunity consists of a humoral and a cellular branch, which are closely interacting.
Koenderman, L., Buurman, W., Daha, M.R.
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2010
Ticks are blood feeding parasites transmitting a wide variety of pathogens to their vertebrate hosts. The vector competence of ticks is tightly linked with their immune system. Despite its importance, our knowledge of tick innate immunity is still inadequate and the limited number of sufficiently characterized immune molecules and cellular reactions ...
Petr, Kopácek +3 more
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Ticks are blood feeding parasites transmitting a wide variety of pathogens to their vertebrate hosts. The vector competence of ticks is tightly linked with their immune system. Despite its importance, our knowledge of tick innate immunity is still inadequate and the limited number of sufficiently characterized immune molecules and cellular reactions ...
Petr, Kopácek +3 more
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Adaptation in the innate immune system and heterologous innate immunity
Cellular and Molecular Life Sciences, 2014The innate immune system recognizes deviation from homeostasis caused by infectious or non-infectious assaults. The threshold for its activation seems to be established by a calibration process that includes sensing of microbial molecular patterns from commensal bacteria and of endogenous signals.
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Cellular and Molecular Life Sciences, 2009
Although platelets are best known as primary mediators of hemostasis, this function intimately associates them with inflammatory processes, and it has been increasingly recognized that platelets play an active role in both innate and adaptive immunity. For example, platelet adhesive interactions with leukocytes and endothelial cells via P-selectin can ...
John W, Semple, John, Freedman
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Although platelets are best known as primary mediators of hemostasis, this function intimately associates them with inflammatory processes, and it has been increasingly recognized that platelets play an active role in both innate and adaptive immunity. For example, platelet adhesive interactions with leukocytes and endothelial cells via P-selectin can ...
John W, Semple, John, Freedman
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Cell and Tissue Research, 2010
The innate immune system is the first line of defense against many common microorganisms, which can initiate adaptive immune responses to provide increased protection against subsequent re-infection by the same pathogen. As a major family of antimicrobial peptides, defensins are widely expressed in a variety of epithelial cells and sometimes in ...
Linda, Hazlett, Minhao, Wu
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The innate immune system is the first line of defense against many common microorganisms, which can initiate adaptive immune responses to provide increased protection against subsequent re-infection by the same pathogen. As a major family of antimicrobial peptides, defensins are widely expressed in a variety of epithelial cells and sometimes in ...
Linda, Hazlett, Minhao, Wu
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Paediatric Respiratory Reviews, 2008
Asthma is a complex disorder and evidence now suggests that it is not solely attributable either to allergy or eosinophilia. Non-eosinophilic asthma accounts for up to one half of all cases and a large proportion have a non-allergic aetiology. The innate immune system responds to a variety of triggers, including viral and bacterial components which are
Simpson, Jodie L. +2 more
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Asthma is a complex disorder and evidence now suggests that it is not solely attributable either to allergy or eosinophilia. Non-eosinophilic asthma accounts for up to one half of all cases and a large proportion have a non-allergic aetiology. The innate immune system responds to a variety of triggers, including viral and bacterial components which are
Simpson, Jodie L. +2 more
openaire +2 more sources