Results 111 to 120 of about 2,570,818 (334)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Stability of gene expression by primary bronchial epithelial cells over increasing passage number

BMC Pulmonary Medicine, 2018
Background An increasing number of studies using primary human bronchial epithelial cells (BECs) have reported intrinsic differences in the expression of several genes between cells from asthmatic and non-asthmatic donors.
Stephen R. Reeves, Kaitlyn A. Barrow, Maria P. White, Lucille M. Rich, Maryam Naushab, Jason S. Debley   +5 more
doaj   +1 more source

The Yonkers Case: Separation of Powers as a Yardstick for Determining Official Immunity [PDF]

, 1989
The author examines the application of the official immunity doctrine to a situation where a federal district court issued contempt citations to local legislators in Yonkers who refused to pass legislation as required by a consent decree.
Walsh, Amy
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

Nature Communications, 2018
Cell type deconvolution from bulk expression data rely on a reference expression matrix. Here, the authors introduce a basis matrix built using data from both healthy and diseased samples profiled on 42 platforms, reducing biases introduced by single ...
Francesco Vallania, Andrew Tam, Shane Lofgren, Steven Schaffert, Tej D. Azad, Erika Bongen, Winston Haynes, Meia Alsup, Michael Alonso, Mark Davis, Edgar Engleman, Purvesh Khatri   +11 more
doaj   +1 more source

Immunity to various species of trypanosomes induced in mice by the cure of experimental infections [PDF]

, 1909
B. T. Terry
openalex   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Directed-Complement Activation as a Novel Immunotherapeutic Approach for HER2-Breast Cancer

ImmunoTargets and Therapy
Carole Seguin-Devaux,1,* Bianca Brandus,1,* Jean-Marc Plesseria,1 Gilles Iserentant,1 Jean-Yves Servais,1 Aubin Pitiot,1 Georgia Kanli,2 Iris Behrmann,3 Rafaëla Schober,1 Jacques Zimmer,1 Jacques HM Cohen,4 Xavier Dervillez1,3 1Department
Seguin-Devaux C, Brandus B, Plesseria JM, Iserentant G, Servais JY, Pitiot A, Kanli G, Behrmann I, Schober R, Zimmer J, Cohen JH, Dervillez X   +11 more
doaj  

Immune Reactions in Rabbits Injected with Micrococci from Acute Poliomyelitis [PDF]

, 1917
G. Mathers, Kenneth W. Howell
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source