Results 111 to 120 of about 2,498,524 (354)
Corticosterone selectively decreases humoral immunity in female eiders during incubation
, 2007 Immunity is hypothesized to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction.
Bourgeon, Sophie, Raclot, Thierry
core +1 more source
ON THE ANALOGY BETWEEN SPONTANEOUS RECOVERIES FROM CANCER AND THE SPECIFIC IMMUNITY INDUCED BY X RAY IRRADIATIONS OF THE LYMPHATIC GLANDS INVOLVED [PDF]
, 1908 H. D. McCulloch
openalex +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Nature Communications, 2018 Cell type deconvolution from bulk expression data rely on a reference expression matrix. Here, the authors introduce a basis matrix built using data from both healthy and diseased samples profiled on 42 platforms, reducing biases introduced by single ...
Francesco Vallania +11 more
doaj +1 more source
PHAGOCYTIC IMMUNITY IN PNEUMOCOCCUS INFECTIONS, AND IN PNEUMONIA WITH RELATION TO THE CRISIS [PDF]
, 1911 SOLOMON STROUSE
openalex +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Immunity to various species of trypanosomes induced in mice by the cure of experimental infections [PDF]
, 1909 B. T. Terry
openalex +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Immune Reactions in Rabbits Injected with Micrococci from Acute Poliomyelitis [PDF]
, 1917 G. Mathers, Kenneth W. Howell
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source