Results 71 to 80 of about 3,965,028 (421)

Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]

open access: yes, 2015
Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Huitema, Edgar   +3 more
core   +2 more sources

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Identification of Plasmodium falciparum translation initiation eIF2β subunit: direct interaction with Protein Phosphatase type 1

open access: yesFrontiers in Microbiology, 2016
Protein phosphatase 1 (PP1c) is one of the main phosphatases whose function is shaped by many regulators to confer a specific location and a selective function for this enzyme. Here, we report that eukaryotic initiation factor 2 of P.
Géraldine eTellier   +11 more
doaj   +1 more source

The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease

open access: yesScientific Reports, 2021
To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-derived intestinal macrophages, to the pathogenesis of inflammatory bowel disease (IBD), it is necessary to identify functionally-different MNP populations.
Pamela B. Wright   +13 more
doaj   +1 more source

Efficient immunization strategies to prevent financial contagion [PDF]

open access: yesScientific Reports 4, 3834, 2014, 2013
Many immunization strategies have been proposed to prevent infectious viruses from spreading through a network. In this study, we propose efficient immunization strategies to prevent a default contagion that might occur in a financial network. An essential difference from the previous studies on immunization strategy is that we take into account the ...
arxiv   +1 more source

Alternative conducted immunity tests [PDF]

open access: yes, 2016
Conducted immunity tests are always performed by the use of CDNs in laboratories in accordance with the standard EN61000-4-6. However, it is not always possible to use CDNs because of some limitations.
Azpúrua Auyanet, Marco Aurelio   +3 more
core   +1 more source

Maternal Immunization [PDF]

open access: yesClinical Infectious Diseases, 2014
Pregnant women, neonates, and infants are at higher risk for severe infections due to vaccine‐preventable diseases. Very young infants rarely respond well to vaccination due to poor immunogenicity and interference from maternal antibody. Maternal immunization protects the mother and fetus from disease and protects the infant through transplacental ...
Helen Y. Chu, Janet A. Englund
openaire   +5 more sources

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

The roles of Toll-like receptor 4 in the pathogenesis of pathogen-associated biliary fibrosis caused by Clonorchis sinensis

open access: yesScientific Reports, 2017
Pathogen-associated biliary fibrosis (PABF) is a type of liver fibrosis characterized by injuries of cholangiocytes and extra cellular matrix (ECM) deposition around bile ducts caused by various bacteria, fungi, virus and parasites.
Chao Yan   +11 more
doaj   +1 more source

Overview of the IL‐1 family in innate inflammation and acquired immunity

open access: yesImmunological Reviews, 2018
The interleukin‐1 (IL‐1) family of cytokines and receptors is unique in immunology because the IL‐1 family and Toll‐like receptor (TLR) families share similar functions.
C. Dinarello
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy