Results 71 to 80 of about 4,133,580 (421)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction
Frontiers in Immunology, 2018 NK cells have potent antitumor capacity. They are enriched in the human liver, with a large subset specialized for tissue-residence. The potential for liver-resident versus liver-infiltrating NK cells to populate, and exert antitumor functions in, human ...
Nicholas J. W. Easom +11 more
doaj +1 more source
BMC Infectious Diseases, 2021 Background Talaromyces marneffei (TM) bloodstream infection is common in Acquired Immunodeficiency Syndrome (AIDS) patients with extreme immunodeficiency in Southeast Asia and South China, however, clinical case study on TM bloodstream infection is ...
Jianjun Sun +13 more
doaj +1 more source
Efficient immunization strategies to prevent financial contagion [PDF]
Scientific Reports 4, 3834, 2014, 2013 Many immunization strategies have been proposed to prevent infectious viruses from spreading through a network. In this study, we propose efficient immunization strategies to prevent a default contagion that might occur in a financial network. An essential difference from the previous studies on immunization strategy is that we take into account the ...
arxiv +1 more source
Alternative conducted immunity tests [PDF]
, 2016 Conducted immunity tests are always performed by the use of CDNs in laboratories in accordance with the standard EN61000-4-6. However, it is not always possible to use CDNs because of some limitations.
Azpúrua Auyanet, Marco Aurelio +3 more
core +1 more source
Clinical Infectious Diseases, 2014 Pregnant women, neonates, and infants are at higher risk for severe infections due to vaccine‐preventable diseases. Very young infants rarely respond well to vaccination due to poor immunogenicity and interference from maternal antibody. Maternal immunization protects the mother and fetus from disease and protects the infant through transplacental ...
Helen Y. Chu, Janet A. Englund
openaire +5 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function
Nature Communications, 2019 Increasing TCR cell surface expression can potentiate T cell responses to low-concentrations of antigen. Here the authors identify aminoacids in human TCR variable domains that impact its surface expression, and demonstrate how editing these residues can
Sharyn Thomas +16 more
doaj +1 more source
Frontiers in Microbiology, 2016 Protein phosphatase 1 (PP1c) is one of the main phosphatases whose function is shaped by many regulators to confer a specific location and a selective function for this enzyme. Here, we report that eukaryotic initiation factor 2 of P.
Géraldine eTellier +11 more
doaj +1 more source
BMC Medicine, 2020 Background There is an urgent need to develop biomarkers that stratify risk of bacterial infection in order to support antimicrobial stewardship in emergency hospital admissions.
Dayle Sampson +16 more
doaj +1 more source