Results 261 to 270 of about 576,905 (342)

Mesenchymal Stem Cell‐Engrafted Bacterial Cellulose and Graphene Oxide Scaffolds Enhance Peripheral Nerve Repair in a Rat Model

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study investigates the use of graphene oxide‐decorated bacterial cellulose (BC/GO) scaffolds combined with mesenchymal stem cells (MSCs) to enhance axonal regeneration after sciatic nerve injury in rats. Graphene oxide is embedded monodispersely into the BC fibrillar matrix.
Ismail Simsek   +5 more
wiley   +1 more source

The Impact of Conjugation Mode and Site on Tubulysin Antibody‐Drug‐Conjugate Efficacy and Stability

open access: yesChemistryOpen, EarlyView.
Two biotransformation events, payload metabolism and deconjugation, are profiled using immuno‐capture ligand‐binding assays and mass spectrometry. The site‐specific antibody‐drug conjugate (ADC) demonstrates superior in vivo efficacy and favorable pharmacokinetics compared to site‐directed or random ADCs.
Sayumi Yamazoe   +13 more
wiley   +1 more source

Bridging immunization gaps: lessons from Zambia's 2024 measles-rubella supplementary immunisation activity. [PDF]

open access: yesFront Public Health
Mwale M   +11 more
europepmc   +1 more source

Advancing dengue vaccine development: Challenges, innovations, and the path toward global protection

open access: yesPediatric Investigation, EarlyView.
Dengue vaccine development faces challenges, including antibody‐dependent enhancement and serotype‐specific immunity. This review highlights licensed vaccines, CYD‐TDV, TAK‐003, and Butantan‐DV, and explores strategies for achieving effective multivalent protection.
Ran Wang   +3 more
wiley   +1 more source

On‐Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles

open access: yesSmall, EarlyView.
A microfluidic platform integrates mRNA synthesis, purification, and LNPs formulation in a continuous, streamlined process. DNA templates are transcribed on‐chip, producing mRNA that is immediately purified and encapsulated into LNPs. This approach enables rapid, scalable production of mRNA‐LNP formulations for research or therapeutic applications ...
Shai Zilberzwige‐Tal   +13 more
wiley   +1 more source

Strengthening Immunization Data: Protocol for the Evaluation of an Electronic Immunization Register.

open access: yesJMIR Res Protoc
Sheel M   +15 more
europepmc   +1 more source

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