Results 141 to 150 of about 322,348 (369)

On the Estimation of the Proportion of True Recent Infections Using the BED Capture Enzyme Immunoassay [PDF]

open access: yesarXiv, 2008
In this short note, we analyze the assumptions made by McDougal et al (2006), both explicit and implicit, in their estimation of the proportion of "true recent infections" using the BED CEIA. This enables us to write down expressions for the sensitivity, short term specificity and long term specificity of a test for recent infection defined by a BED ...
arxiv  

Deep Learning‐Enhanced Hand‐Driven Microfluidic Chip for Multiplexed Nucleic Acid Detection Based on RPA/CRISPR

open access: yesAdvanced Science, EarlyView.
Efficient R‐CHIP HR‐HPV Screening System: The R‐CHIP system utilizes the RPA/CRISPR method, a hand‐driven centrifugal microfluidic device, a smartphone micro‐imaging system, and the ResNet‐18 deep‐learning algorithm to simplify the sample detection process, ensure accurate results, and reduce costs.
Tao Xu   +11 more
wiley   +1 more source

The generation of multi-laminar reagent streams for rapid, sequential (bio)chemical reactions on magnetic particles in a continuous flow microreactor [PDF]

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +5 more
core  

A simple device for multiplex ELISA made from melt-extruded plastic microcapillary film [PDF]

open access: yes, 2011
We present a simple device for multiplex quantitative enzyme-linked immunosorbant assays (ELISA) made from a novel melt-extruded microcapillary film (MCF) containing a parallel array of 200µm capillaries along its length.
Abramoff   +29 more
core   +2 more sources

ABO Blood-Typing Using an Antibody Array Technique Based on Surface Plasmon Resonance Imaging

open access: yesSensors, 2013
In this study, readily available antibodies that are used in standard agglutination tests were evaluated for their use in ABO blood typing by a surface plasmon resonance imaging (SPR imaging) technique.
Toemsak Srikhirin   +9 more
doaj   +1 more source

Chemiluminescent immunoassay technology: what does it change in autoantibody detection?

open access: yesAutoimmunity Highlights, 2017
Diagnostic technology is rapidly evolving, and over the last decade, substantial progress has been made even for the identification of antibodies, increasingly approaching this type of diagnostic to that of automated clinical chemistry laboratory.
L. Cinquanta, D. Fontana, N. Bizzaro
semanticscholar   +1 more source

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim   +19 more
wiley   +1 more source

Limitations of Label-Free Sensors in Serum Based Molecular Diagnostics [PDF]

open access: yesarXiv, 2015
Immunoassay formats applicable for clinical or point-of-care diagnostics fall into two broad classes. One which uses labeled secondary antibodies for signal transduction and the other which does not require the use of any labels. Comparison of the limits of detection (LoD) reported by these two sensing approaches over a wide range of detection ...
arxiv  

A Practical Guide to Immunoassay Method Validation

open access: yesFrontiers in Neurology, 2015
Biochemical markers have a central position in the diagnosis and management of patients in clinical medicine, and also in clinical research and drug development, also for brain disorders, such as Alzheimer’s disease. The enzyme-linked immunosorbent assay
U. Andreasson   +22 more
semanticscholar   +1 more source

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

open access: yesAdvanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao   +15 more
wiley   +1 more source

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