Results 191 to 200 of about 322,348 (369)
Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models
Animal Models and Experimental Medicine, EarlyView.We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv +12 more
wiley +1 more source
Label‐Free Microscale Technologies for Isolation of Heterogeneous Circulating Tumor Cells
Advanced NanoBiomed Research, EarlyView.The isolation of circulating tumor cells (CTCs) from liquid biopsy samples is crucial for cancer treatment and monitoring. This review evaluates primary label‐free isolation methods for capturing heterogeneous CTCs and examines their potential to provide deeper insights into tumor heterogeneity and dynamics of cancer progression.
Gürhan Özkayar +5 more
wiley +1 more source
Antigen requirements, sensitivity, and specificity of enzyme immunoassays for measles and rubella viral antibodies [PDF]
, 1979 Bagher Forghani, Nathalie J. Schmidt
openalex +1 more source
Functional Synovium‐Based 3D Models in the Context of Human Disease and Inflammation
Advanced NanoBiomed Research, EarlyView.The synovium is key to joint function but is often affected by diseases like rheumatoid arthritis. Finding better treatments is challenging because current lab models do not fully mimic real tissues. New 3D technologies, like bioprinting, offer better methods to study these diseases, improve drug testing, and develop personalized treatments, bringing ...
Amelia Heslington +3 more
wiley +1 more source
Diagnosis of invasive candidosis by enzyme immunoassay of serum antigen. [PDF]
, 1977 R. Warrén +5 more
openalex +1 more source
Analysis &Sensing, EarlyView.On‐paper enzyme‐linked and metal‐linked immunosorbent assays (p‐ELISA and p‐MeLISA, respectively) were developed for the assay of carcinoembryonic antigen (CEA) in serum. These approaches are based on bio‐conjugated paper disks as analytical platform.
Electra Mermiga +4 more
wiley +1 more source
Discrepancies Between Radioimmunoassays and Bioassay for Rat FSH: Evidence that Androgen Treatment and Withdrawal Can Alter Biossay—Immunoassay Ratios1 [PDF]
, 1973 N. D. DIEBEL +2 more
openalex +1 more source
Arthritis &Rheumatology, EarlyView.Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm +18 more
wiley +1 more source
Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism
Arthritis &Rheumatology, Accepted Article.Background JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but TYK2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn's Disease, which highlights the complex role for JAK‐STAT signaling in different inflammatory processes. In this study, we investigated
Sami Giryes +14 more
wiley +1 more source