Background: Vaccination is an extremely safe public health intervention, but rare IgE-mediated adverse events must be identified to avoid the risk of anaphylaxis in the event of reexposure.
Luciana Gomes Pedro Brandão, PhD, MSc, MD +10 more
doaj +1 more source
Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease, [PDF]
As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations.
Lucas Campos Garcia +3 more
doaj +1 more source
Replacement, Reduction and Refinement of Animal Testing in the Quality Control of Human Vaccines [PDF]
Vaccines are recognised as a highly cost effective tool for preventing infectious diseases. They are derived from biological sources and due to the complexity of composition and heterogeneity of products, vaccine lots undergo legally required quality ...
HALDER MARIA ELISABETH
core +1 more source
Special immunobiologicals’ schedule applied to infants at a reference service in Ceará -
Objective: To analyze the vaccine schedule for preterm infants in a program of special immunobiologicals. Methods: A documental study conducted at a Reference Center of Special Immunobiologicals (CREATE) situated in a general hospital of tertiary care ...
Vera Lúcia Bezerra Oliveira +2 more
doaj +1 more source
Role of AMPK Throughout Meiotic Maturation in the Mouse Oocyte: Evidence for Promotion of Polar Body Formation and Suppression of Premature Activation [PDF]
This study was conducted to assess the role of AMPK in regulating meiosis in mouse oocytes from the germinal vesicle stage to metaphase II. Exposure of mouse cumulus cell-enclosed oocytes (CEO) and denuded oocytes (DO) during spontaneous maturation in ...
Davis, Christopher C. +2 more
core +2 more sources
Fatty Acid Oxidation and Meiotic Resumption in Mouse Oocytes [PDF]
We have examined the potential role of fatty acid oxidation (FAO) in AMP-activated protein kinase (AMPK)-induced meiotic maturation. Etomoxir and malonyl CoA, two inhibitors of carnitine palmitoyl transferase-1 (CPT1), and thus FAO, blocked meiotic ...
Downs, Stephen +2 more
core +2 more sources
CLO: The cell line ontology [PDF]
Background Cell lines have been widely used in biomedical research. The community-based Cell Line Ontology (CLO) is a member of the OBO Foundry library that covers the domain of cell lines. Since its publication two years ago, significant
Athey, Brian D +24 more
core +6 more sources
Although in the last years poliovirus (PV) transmission has been reported at the lowest levels ever recorded, the spread of virus from endemic countries endures; the high levels of immigration flows across the Mediterranean Sea jeopardize Italy for PV ...
Laura Pellegrinelli +7 more
doaj +1 more source
Inhibition of free radical generation and improved survival by protection of the hepatic microvascular endothelium by targeted erythrocytes in orthotopic rat liver transplantation [PDF]
The capacity of specifically targeted erythrocytes to inhibit free radical—mediated injury to the endothelial cell after cold preservation, and improve liver function was studied in two experimental models: An isolated perfused rat liver (IPRL) system ...
Demetris, AJ +8 more
core +1 more source
Usability of the ConectAPS-CRIE platform for management of special immunobiologicals in Primary Health Care [PDF]
Objective: To evaluate the usability of the ConectAPS-CRIE platform in the management of special immunobiologicals in primary health care by nursing professionals.
Cláudia Carolina Costa Braga +1 more
doaj +1 more source

