Lactiplantibacillus plantarum as a Potential Adjuvant and Delivery System for the Development of SARS-CoV-2 Oral Vaccines [PDF]
Microorganisms, 2021 The most important characteristics regarding the mucosal infection and immune responses against the Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) as well as the current vaccines against coronavirus disease 2019 (COVID-19) in development or use ...
Julio Villena +5 more
doaj +2 more sources
Modulation of intestinal TLR4-inflammatory signalling pathways by probiotic microorganisms: lessons learned from Lactobacillus jensenii TL2937 [PDF]
Frontiers in Immunology, 2014 The intestinal mucosa plays a critical role in the host's interactions with innocuous commensal microbiota and invading pathogenic microorganisms. Intestinal epithelial cells (IECs) and gut associated immune cells recognize the bacterial components via ...
Julio eVillena, Haruki eKitazawa
doaj +2 more sources
Immunobiotic Lactobacilli Improve Resistance of Respiratory Epithelial Cells to SARS-CoV-2 Infection [PDF]
Pathogens, 2021 Previously, we reported that immunomodulatory lactobacilli, nasally administered, beneficially regulated the lung antiviral innate immune response induced by Toll-like receptor 3 (TLR3) activation and improved protection against the respiratory pathogens,
Md. Aminul Islam +9 more
doaj +4 more sources
Lactobacillus delbrueckii CRL 581 Differentially Modulates TLR3-Triggered Antiviral Innate Immune Response in Intestinal Epithelial Cells and Macrophages [PDF]
Microorganisms, 2021 Lactobacillus delbrueckii subsp. lactis CRL 581 beneficially modulates the intestinal antiviral innate immune response triggered by the Toll-like receptor 3 (TLR3) agonist poly(I:C) in vivo.
Mariano Elean +11 more
doaj +2 more sources
Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host Cells [PDF]
Microorganisms, 2016 Researchers have demonstrated that lactic acid bacteria (LAB) with immunomodulatory capabilities (immunobiotics) exert their beneficial effects through several molecules, including cell wall, peptidoglycan, and exopolysaccharides (EPS), that are able to ...
Jonathan Laiño +3 more
doaj +2 more sources
Modulation of respiratory TLR3-antiviral response by probiotic microorganisms: lessons learned from Lactobacillus rhamnosus CRL1505 [PDF]
Frontiers in Immunology, 2014 Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract illness in infants and young children. Host immune response is implicated in both protective and immunopathological mechanisms during RSV infection. Activation of Toll-like
Haruki eKitazawa, Julio eVillena
doaj +2 more sources
, 2022 Abstract Background Non-alcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease worldwide that can progress to liver fibrosis (LF). Probiotics have beneficial roles in reducing intestinal inflammation and gut-associated diseases, but their effects and mechanisms beyond the gut in attenuating the progression of LF are ...
Paulraj Kanmani +5 more
openaire +2 more sources
A Novel Immunobiotics Bacteroides dorei Ameliorates Influenza Virus Infection in Mice [PDF]
Frontiers in Immunology, 2022 ObjectiveProbiotics can modulate immune responses to resist influenza infection. This study aims to evaluate the anti-viral efficacy of B. dorei.MethodsC57BL/6J mice were infected with influenza virus together with treatment of PBS vehicle, B.
Liqiong Song +11 more
doaj +3 more sources
MODULATION OF SYSTEMIC INNATE AND ADAPTIVE IMMUNE PARAMETERS IN WEANED PIGS BY SINGLE ORAL APPLICATION OF IMMUNOBIOTICS [PDF]
Slovenian Veterinary Research, 2018 The aims of this study were to evaluate the effects of peroral treatment of 4-week old pigs at weaning (Day 0) with a single dose of levamisole (LEVA) or polyoxyethyle-polyoxypropylene (POE-POP), well known immunobiotics (IBC) and promising alternatives ...
Hrvoje Valpotić +10 more
doaj +2 more sources
Advances in Microbial Exopolysaccharides: Present and Future Applications [PDF]
BiomoleculesMicrobial exopolysaccharides (EPSs) are receiving growing interest today, owing to their diversity in chemical structure and source, multiple functions, and immense potential applications in many food and non-food industries.
Huu-Thanh Nguyen +5 more
doaj +2 more sources