Results 61 to 70 of about 17,783 (180)

Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro‐inflammatory cytokines

Anaesthesia, Volume 81, Issue 8, Page 1079-1090, August 2026.
Summary Introduction Labour epidural analgesia is the most effective method for intrapartum pain relief and is associated with improved maternal outcomes. However, concerns have been raised regarding potential associations between labour epidural analgesia and adverse psycho‐emotional outcomes in children. Evidence from large epidemiological studies is
Sana Asif, Hsing‐Fen Tu, Richard A. White, Birgitta Birgisdottir, Miklos Lipcsey, Martin F. Bjurström, Alkistis Skalkidou   +6 more
wiley   +1 more source

Genetic Diversity and Haplotype Architecture of Non‐Classical HLA Class I Genes in the Japanese Population

HLA, Volume 108, Issue 2, August 2026.
ABSTRACT The non‐classical Class I genes (HLA‐E, HLA‐F and HLA‐G) show limited protein‐level diversity; however, full‐length analyses that include regulatory and noncoding regions have not been sufficiently performed in East Asian populations. We designed new primers for long‐range PCR and conducted PacBio SMRT sequencing to generate full‐length gene ...
Ikue Ito‐Naito, Seik‐Soon Khor, Tetsuya Sato, Shunichi Wakabayashi, Daisuke Kinoshita, Naoya Kubo, Yosuke Omae, Katsushi Tokunaga, Hiroshi Hayashi   +8 more
wiley   +1 more source

A Comprehensive Analysis of the Genomic and Expressed Repertoire of the T-Cell Receptor Beta Chain in Equus caballus

Animals
In this paper, we report a comprehensive and consistent annotation of the locus encoding the β-chain of the equine T-cell receptor (TRB), as inferred from recent genome assembly using bioinformatics tools.
Rachele Antonacci, Francesco Giannico, Roberta Moschetti, Angela Pala, Anna Caputi Jambrenghi, Serafina Massari   +5 more
doaj   +1 more source

Immunity-mediated diseases and human immunogenetics (accomplishments and prospects)

Сахарный диабет, 2016
Type 1 diabetes mellitus (T1DM) was used from the viewpoint of human immunogenetics as an example of the most widely studied immunity-mediated disease. This was done in order to develop, approve and implement a new clinical approach to determine immunity-
Ivan Ivanovich Dedov, Rakhim Musaevich Khaitov, Leonid Petrovich Alexeev   +2 more
doaj   +1 more source

IMGT/mAb-KG: the knowledge graph for therapeutic monoclonal antibodies

Frontiers in Immunology
IntroductionTherapeutic monoclonal antibodies (mAbs) have demonstrated promising outcomes in diverse clinical indications, including but not limited to graft rejection, cancer, and autoimmune diseases lately.Recognizing the crucial need for the ...
Gaoussou Sanou, Gaoussou Sanou, Taciana Manso, Konstantin Todorov, Véronique Giudicelli, Patrice Duroux, Sofia Kossida   +6 more
doaj   +1 more source

Immunogenetics of chronic lymphocytic leukemia

Indian Journal of Pathology and Microbiology, 2017
Introduction: Cytogenetic aberrations as well as presence of IGVH mutations are the underlying reason for clinical heterogeneity in Chronic Lymphocytic Leukemia (CLL).
Nikhil Patkar, Nikhil Rabade, Pratibha Amare Kadam, Falguni Mishra, Aditi Muranjan, Prashant Tembhare, Shruti Chaudhary, Swapnali Joshi, Hasmukh Jain, Uma Dangi, Bhausaheb Bagal, Navin Khattry, Hari Menon, Sumeet Gujral, Manju Sengar, P G Subramanian   +15 more
doaj   +1 more source

Immunogenetics of Systemic Sclerosis

Genes
Systemic sclerosis (SSc) is a rare autoimmune connective tissue disorder characterized by massive fibrosis, vascular damage, and immune imbalance. Advances in rheumatology and immunology over the past two decades have led to a redefinition of systemic sclerosis, shifting from its initial perception as primarily a “hyperfibrotic” state towards a ...
Olga Gumkowska-Sroka, Kacper Kotyla, Przemysław Kotyla   +2 more
openaire   +3 more sources

Plasma PFDN2 suppresses head and neck squamous cell carcinoma progression by restricting CD64 on monocyte-driven inflammatory microenvironments

Frontiers in Immunology
BackgroundHead and neck squamous cell carcinoma (HNSC) is a highly heterogeneous malignancy with poor prognosis and frequent recurrence. Beyond tumor-intrinsic alterations, the immune microenvironment plays a decisive role in tumor initiation and ...
Chen Feng, Ce Li, Dapeng Lei
doaj   +1 more source

Editorial: Role of the antigen receptor in the pathogenesis of B-cell lymphoid malignancies

Frontiers in Oncology, 2023
Andreas Agathangelidis, Manlio Ferrarini, Franco Fais, Franco Fais   +3 more
doaj   +1 more source

Biomarkers and genetic factors beyond hypocretin-1 in the diagnostics of narcolepsy

Journal of Clinical Sciences
Narcolepsy is a chronic sleep-wake disorder usually diagnosed by polysomnography, multiple sleep latency testing, and laboratory assessment. One such laboratory approach involves measuring hypocretin-1 in cerebrospinal fluid.
Beeravolu Harshith Reddy, Babaji Ghewade, Ulhas Jadhav, Vivek Dipakrao Alone   +3 more
doaj   +1 more source