Results 41 to 50 of about 21,232 (243)

T Cell Plasticity in Systemic Lupus Erythematosus Revealed by Large‐Scale T Cell Receptor Repertoire and Transcriptome Studies

open access: yesArthritis &Rheumatology, EarlyView.
Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi   +11 more
wiley   +1 more source

Immunogenetics of Aging’: report on the activities of the 15th International HLA and Immunogenetics Working Group and 15th International HLA and Immunogenetics Workshop [PDF]

open access: yes, 2011
‘Immunogenetics of Aging’ is a component that was first included in the 14th International HLA and Immunogenetics Workshop (IHIWS) and developed further within the 15th Workshop.
Pawelec, G   +31 more
core   +2 more sources

Gingival inflammation and plaque accumulation affect therapeutic outcomes in patients with acne vulgaris

open access: yesJournal of Periodontology, EarlyView.
Abstract Background We hypothesized that acne vulgaris (AV) and gingivitis were associated through systemic inflammatory mechanisms, sharing common etiological factors. This study aimed to identify the association between AV and gingivitis and to assess changes in acne severity in relation to changes in the plaque index (PI).
Ömer Faruk Okumuş   +2 more
wiley   +1 more source

The Immunogenetic Conundrum of Preeclampsia [PDF]

open access: yesFrontiers in Immunology, 2018
Pregnancy is an immunological challenge to the mother. The fetal tissues including the placenta must be protected from activation of the maternal immune system. On the other hand, the placental tissue sheds into the maternal circulation and must be adequately identified and phagocytized by the maternal immune system.
A. Inkeri Lokki   +6 more
openaire   +4 more sources

Toll-Like Receptor-1 Single-Nucleotide Polymorphism 1805T/G Is Associated With Predisposition to Multibacillary Tuberculosis

open access: yesFrontiers in Immunology, 2018
Tuberculosis (TB), caused by mycobacterial species of the Mycobacterium tuberculosis complex, is a serious global health issue. Brazil is among the 22 countries with the highest number of TB cases, and the state of Amazonas has the highest incidence of ...
Raphaela Honorato Barletta-Naveca   +19 more
doaj   +1 more source

Pain and Cellular Migration Induced by Bothrops jararaca Venom in Mice Selected for an Acute Inflammatory Response: Involvement of Mast Cells

open access: yesFrontiers in Immunology, 2022
Bothrops jararaca venom (BjV) can induce mast cell degranulation. In order to investigate the role of mast cells and the interference of the host genetic background in the inflammation induced by BjV, we have used mouse strains selected for maximal ...
Fernanda V. Kondo   +10 more
doaj   +1 more source

Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds

open access: yesThe Laryngoscope, EarlyView.
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter   +6 more
wiley   +1 more source

The MHC Class Ia Genes in Chenfu’s Treefrog (Zhangixalus chenfui) Evolved via Gene Duplication, Recombination, and Selection

open access: yesAnimals, 2019
The molecular mechanisms underlying the evolution of adaptive immunity-related proteins can be deduced by a thorough examination of the major histocompatibility complex (MHC).
Hu Chen   +8 more
doaj   +1 more source

Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro‐inflammatory cytokines

open access: yesAnaesthesia, EarlyView.
Summary Introduction Labour epidural analgesia is the most effective method for intrapartum pain relief and is associated with improved maternal outcomes. However, concerns have been raised regarding potential associations between labour epidural analgesia and adverse psycho‐emotional outcomes in children. Evidence from large epidemiological studies is
Sana Asif   +6 more
wiley   +1 more source

IMGT, the international ImMunoGeneTics database

open access: yes, 2001
International audienceIMGT, the international ImMunoGeneTics database, freely available at http://imgt.cines.fr:8104, was created in 1989 at the Université Montpellier II, CNRS, Montpellier, France, and is a high quality integrated information system ...
M.-P. Lefranc, Lefranc, Marie-Paule
core   +1 more source

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