Results 51 to 60 of about 17,783 (180)
Immunogenomics: Molecular hide and seek
Similar to other classical science disciplines, immunology has been embracing novel technologies and approaches giving rise to specialised sub-disciplines such as immunogenetics and, more recently, immunogenomics, which, in many ways, is the genome-wide ...
Miretti Marcos M, Beck Stephan
doaj +1 more source
Abstract Background Although widely studied and reported for more than 30 years, the molecular basis of Rh D‐negativity has remained unexplored in several regions of the world, including in Indonesia, Southeast Asia. Study Design and Methods A subset of 436 Indonesian blood donors originally typed D‐negative (D–) by routine serological testing was ...
Tonny Wongso +11 more
wiley +1 more source
Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth +3 more
wiley +1 more source
Identifying the immune interactions underlying HLA class I disease associations
Variation in the risk and severity of many autoimmune diseases, malignancies and infections is strongly associated with polymorphisms at the HLA class I loci.
Bisrat J Debebe +10 more
doaj +1 more source
Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter +6 more
wiley +1 more source
Abstract Somatic mutations and antibody clone selection occur in B‐cell hyper‐evolution over extremely brief periods of time. Herein, we developed a technique for antibody screening by immunizing alpacas with antigens and observing antibody sequence transitions over time, a method we named Tracking the Evolution of Antibodies over time.
Yoko Akazawa‐Ogawa +7 more
wiley +1 more source
Immunogenetic analysis of disease susceptibility has been encouraged by the identification of strong HLA associations with several diseases of uncertain cause. Weaker HLA associations exist with a large number of infectious and non-infectious diseases and the mechanisms of these effects are beginning to be uncovered.
openaire +2 more sources
The Gap Between Prescription and Practice: Adrenaline Autoinjector Carriage in an Australian Cohort
Clinical &Experimental Allergy, EarlyView.
Jason Chun Lao +6 more
wiley +1 more source
ABSTRACT Background and Aims The HLA‐B*15:02 allele is related to a high risk of severe cutaneous adverse drug reactions (SCARs) in patients taking certain antiepileptic drugs. However, its prevalence in the Asian population and the number of drugs linked to SCARs due to the carriage of this variant are relatively underexplored.
Mohitosh Biswas +3 more
wiley +1 more source
ABSTRACT Background Immune surveillance is increasingly recognized as a determinant of clonal selection in Philadelphia chromosome‐negative myeloproliferative neoplasms (MPN). While HLA‐restricted adaptive immune effects have been described, the contribution of inherited variation in natural killer (NK)‐cell regulatory pathways remains less well ...
Velizar Shivarov +3 more
wiley +1 more source

