Results 51 to 60 of about 17,783 (180)

Immunogenomics: Molecular hide and seek

open access: yesHuman Genomics, 2006
Similar to other classical science disciplines, immunology has been embracing novel technologies and approaches giving rise to specialised sub-disciplines such as immunogenetics and, more recently, immunogenomics, which, in many ways, is the genome-wide ...
Miretti Marcos M, Beck Stephan
doaj   +1 more source

Investigating the molecular basis of the serological Rh D‐negative phenotype in Indonesia: nature, frequency, and impact for diagnostics

open access: yesTransfusion, EarlyView.
Abstract Background Although widely studied and reported for more than 30 years, the molecular basis of Rh D‐negativity has remained unexplored in several regions of the world, including in Indonesia, Southeast Asia. Study Design and Methods A subset of 436 Indonesian blood donors originally typed D‐negative (D–) by routine serological testing was ...
Tonny Wongso   +11 more
wiley   +1 more source

Evaluation for endotoxin in intraocular materials used during phacoemulsification surgery using a recombinant factor C assay

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 481-485, March 2025.
Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth   +3 more
wiley   +1 more source

Identifying the immune interactions underlying HLA class I disease associations

open access: yeseLife, 2020
Variation in the risk and severity of many autoimmune diseases, malignancies and infections is strongly associated with polymorphisms at the HLA class I loci.
Bisrat J Debebe   +10 more
doaj   +1 more source

Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 3895-3906, September 2026.
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter   +6 more
wiley   +1 more source

Optimization of antibody binding by adjusting thermodynamic stability during the maturation of antibody affinities

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Somatic mutations and antibody clone selection occur in B‐cell hyper‐evolution over extremely brief periods of time. Herein, we developed a technique for antibody screening by immunizing alpacas with antigens and observing antibody sequence transitions over time, a method we named Tracking the Evolution of Antibodies over time.
Yoko Akazawa‐Ogawa   +7 more
wiley   +1 more source

Immunogenetics and genomics

open access: yesThe Lancet, 2001
Immunogenetic analysis of disease susceptibility has been encouraged by the identification of strong HLA associations with several diseases of uncertain cause. Weaker HLA associations exist with a large number of infectious and non-infectious diseases and the mechanisms of these effects are beginning to be uncovered.
openaire   +2 more sources

The Gap Between Prescription and Practice: Adrenaline Autoinjector Carriage in an Australian Cohort

open access: yes
Clinical &Experimental Allergy, EarlyView.
Jason Chun Lao   +6 more
wiley   +1 more source

Investigation of the Prevalence of the HLA‐B*15:02 Allele in the Asian Populations: A Comprehensive Analysis Through Using AFND

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims The HLA‐B*15:02 allele is related to a high risk of severe cutaneous adverse drug reactions (SCARs) in patients taking certain antiepileptic drugs. However, its prevalence in the Asian population and the number of drugs linked to SCARs due to the carriage of this variant are relatively underexplored.
Mohitosh Biswas   +3 more
wiley   +1 more source

Inhibitory HLA‐C/KIR2DL2 Interactions and KIR Allelic Polymorphisms Are Associated With Susceptibility to Philadelphia Chromosome‐Negative Myeloproliferative Neoplasms

open access: yeseJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background Immune surveillance is increasingly recognized as a determinant of clonal selection in Philadelphia chromosome‐negative myeloproliferative neoplasms (MPN). While HLA‐restricted adaptive immune effects have been described, the contribution of inherited variation in natural killer (NK)‐cell regulatory pathways remains less well ...
Velizar Shivarov   +3 more
wiley   +1 more source

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