Results 241 to 250 of about 7,237,819 (287)

A Deep-Red-Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy Inducing Immunogenic Cell Death. [PDF]

Angew Chem Int Ed Engl
Zhang Y, Mesdom P, Izquierdo-García E, António JPM, Gao R, Saubaméa B, Seguin J, Moinard M, Arnoux P, Frochot C, Cariou K, Doan BT, Gasser G.   +12 more
europepmc   +1 more source

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

Advanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan, Bin Chen, Yanqing Wang, Yuxi Hou, Zhenlin Ma, Zini Yang, Xia Yin, Yiling Chen, Litao Huang, Menghan Cai, Xinlin Liu, Yi Zhun Zhu, Li Ye   +12 more
wiley   +1 more source

Enhancing immunogenic cell death by targeting the GPX4-ZP3 immune checkpoint. [PDF]

Oncoimmunology
Tang D, Kang R, Liu P, Kroemer G.
europepmc   +1 more source

Polyphosphate Copper Nanospheres Drive Mitochondrial Metabolic Reprogramming via Calcium Phase Separation for Self‐Sensitizing Cuproptosis

Advanced Science, EarlyView.
This study developed polyphosphate (polyP)‐based nanostructures that enable calcium‐mediated metabolic reprogramming via liquid–liquid phase separation (LLPS). Released polyP undergoes LLPS with Ca2+, suppressing glycolytic flux and enhancing mitochondrial metabolism effectively.
Jing Wang, Xinyang Zhao, Zifeng Huang, Jingyi Zhang, Yucheng Tao, Yong Huang, Zijian Guo, Lei Dong, Xiuxiu Wang, Jing Zhao, Wei Wei   +10 more
wiley   +1 more source

The interplay between autophagy and immunogenic cell death: nanomaterial-based strategies for cancer immunotherapy. [PDF]

J Nanobiotechnology
Khorrami M, Fadaie M, Dizaji SR, Davoodi A, Asghari R, Shen J, Rahimmanesh I, Sethi G, Makvandi P.   +8 more
europepmc   +1 more source

CaMKIIδ Phosphorylates AUP1 to Promote Pancreatic Tissue Repair and Acinar‐to‐Ductal Metaplasia Formation via Mediating PERK‐Dependent Unfolded Protein Responses

Advanced Science, EarlyView.
CaMKIIδ–AUP1 signaling maintains PERK‐dependent ER homeostasis during ADM‐mediated pancreatic repair. ABSTRACT Pancreatic repair after acute pancreatitis (AP) is essential for restoring tissue integrity, but the intrinsic mechanisms coordinating acinar plasticity and regeneration remain poorly understood.
Yonghao Chen, Ziying Han, Zihan Yang, Jie Wu, Kaixin Peng, Xiuli Zhang, Bintao Qiu, Jianqiang Wu, Xiaomin Hu, Dong Wu, Li Wen   +10 more
wiley   +1 more source

Enfortumab vedotin induces immunogenic cell death and shows enhanced preclinical antitumor activity when combined with a PD-1 inhibitor. [PDF]

Cell Rep Med
Olson DJ, Liu BA, Younan P, Blahnik-Fagan G, Stacey RG, Gosink J, Snead K, Tenn E, Hensley K, Sahetya D, Nesterova A, Zaval M, Cao A, O'Day C, Heiser RA, Lewis TS, Gardai SJ, Nakazawa T, Shimazaki M, Carosino C, Szeto GL, Sandall S.   +21 more
europepmc   +1 more source

Chimeric biohybrid nanovesicles induce immunogenic cell death for targeted and immune-potentiated glioblastoma therapy. [PDF]

Asian J Pharm Sci
Zhu X, Xing Y, Jin W, Geng H, Li F, Li Y, Zhang H, Wu C, Chen C, Wu Z.   +9 more
europepmc   +1 more source

Immunogenic cell death in cold tumors: transforming immune-excluded tumors into immunotherapy-sensitive lesions. [PDF]

Front Pharmacol
Zhao H, Dai S.
europepmc   +1 more source