Results 251 to 260 of about 129,949 (299)

Immunogenic cell death biomarkers for sepsis diagnosis and mechanism via integrated bioinformatics. [PDF]

Sci Rep
Li G, Tian X, Wei E, Zhang F, Liu H.
europepmc   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Dual-Targeted Biomimetic Nanoparticles for Enhanced Delivery of Polyphyllin B Synergistically Induce Ferroptosis and Immunogenic Cell Death in Gastric Cancer. [PDF]

ACS Appl Mater Interfaces
Zu D, Yao J, Li X, Huang Y, Hu C, Deng M, Bao Q, Shi Y, Ye Z, Cheng X.   +9 more
europepmc   +1 more source

Near-Infrared Light-Responsive Copper Selenide Nanoparticle-Loaded Calcium Silicate Cement Induces Immunogenic Cell Death in Osteosarcoma. [PDF]

Int J Nanomedicine
Liu R, Sun R, Xue Y, Zhou Y, Zhan L, Li Y, Tian Y, Wang C, Feng W, Chang B, Fan B, Gao Q.   +11 more
europepmc   +1 more source

The anticancer thiosemicarbazone triapine exerts immune-enhancing activities via immunogenic cell death induction and FAS upregulation. [PDF]

Exp Hematol Oncol
Stiller B, Stefanelli A, Schueffl H, Mathuber M, Skorokhyd N, Gufler J, Pirker C, Holcmann M, Panchuk R, Sibilia M, Marko D, Berger W, Kowol CR, Hager S, Heffeter P.   +14 more
europepmc   +1 more source

Sodium butyrate enhances sorafenib-induced ferroptosis and immunogenic cell death by modulating IRF2-Oasl2-cGAS pathway in colorectal cancer. [PDF]

Mater Today Bio
Xiang Y, Zheng J, Zhao X, Zhou L, Yan Q, Ma Y, Zhou Y, Jiang P, Fang Y, Li W, Pan Y, Tao H, Li W, Xiang F, Hua Y, Li Y, Zheng C, Ge W, Li Y, Yan S, Zhu Y, Xu G.   +21 more
europepmc   +1 more source

Cantharidin-Loaded Nanomedicine Modified with Amphiphilic Peptides Induce Immunogenic Cell Death to Enhance PD-1 Blockade. [PDF]

ACS Appl Mater Interfaces
Tang Y, Jiang Q, Chen R, Wu S, Luo Y, Huang X, Yu G, Shao C.   +7 more
europepmc   +1 more source

A Triple Threat Against Ovarian Cancer: Os(II)-Pt(IV)-Ceritinib Conjugates for Photodynamic Therapy, Chemotherapy, and Immunogenic Cell Death Induction. [PDF]

Angew Chem Int Ed Engl
Redrado M, Acharya S, Mesdom P, Babu T, Southwell JW, Oliveira LS, Hidalgo S, Arnoux P, Frochot C, Gibson D, Gasser G.   +10 more
europepmc   +1 more source

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Immunogenic cell stress and death

Nature Immunology, 2022
Dying mammalian cells emit numerous signals that interact with the host to dictate the immunological correlates of cellular stress and death. In the absence of reactive antigenic determinants (which is generally the case for healthy cells), such signals may drive inflammation but cannot engage adaptive immunity.
Guido Kroemer, Claudia Galassi, Laurence Zitvogel, Lorenzo Galluzzi   +3 more
openaire   +2 more sources