Results 101 to 110 of about 456,969 (387)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors

open access: yesFrontiers in Immunology
The global market for therapeutic peptides is projected to continue to grow at a fast pace in the coming years in response to high demand for these products. The increasing complexity of chemical and recombinant peptide manufacturing processes may impact
Montserrat Puig, Sophie Shubow
doaj   +1 more source

Expression and Immunogenicity of Recombinant African Swine Fever Virus Proteins Using the Semliki Forest Virus

open access: yesFrontiers in Veterinary Science, 2022
African swine fever virus (ASFV) is a large DNA virus belonging to the Asfarviridae family that damages the immune system of pigs, resulting in the death or slaughter of millions of animals worldwide.
Niran Fang   +10 more
doaj   +1 more source

Immunogenicity of human spermatozoa [PDF]

open access: yes, 2008
Investigation and experimental design of the study was basically aimed at developing insight into the antigenicity of spermatozoa-associated proteins. Apart from studying the natural antigenicity of washed whole spermatozoa, their immunogenicity was also
Jhinuk Chatterjee, Sukumar Chattopadhyay
core   +1 more source

Human and bovine respiratory syncytial virus vaccine research and development [PDF]

open access: yes, 2008
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine   +2 more
core   +1 more source

Immunogenicity of the BNT162b2 vaccine in frail or disabled nursing home residents: COVID‐A study

open access: yesJournal of The American Geriatrics Society, 2021
The safety and immunogenicity of the BNT162b2 coronavirus disease 2019 (COVID‐19) vaccine in older adults with different frailty and disability profiles have not been well determined. Our objective was to analyze immunogenicity of the BNT162b2 mRNA COVID‐
Sergio Salmerón Ríos   +14 more
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Comparative analysis of the immunogenicity of monovalent and multivalent rotavirus immunogens

open access: yesPLOS ONE, 2017
The strategies for developing rotavirus (RV) vaccines have always been controversial. At present, both the monovalent RV vaccine and the multivalent RV vaccine have displayed excellent safety and efficacy against RV infection and shown cross-reactive immunity, which laid the question whether the multivalent RV vaccine could be replaced by the ...
Xianglian Niu   +9 more
openaire   +5 more sources

In Silico Methods in Antibody Design

open access: yesAntibodies, 2018
Antibody therapies with high efficiency and low toxicity are becoming one of the major approaches in antibody therapeutics. Based on high-throughput sequencing and increasing experimental structures of antibodies/antibody-antigen complexes, computational
Jun Zhao   +3 more
doaj   +1 more source

Humoral Response to BNT162b2 Vaccine Against SARS-CoV-2 Variants Decays After Six Months

open access: yesFrontiers in Immunology, 2022
SARS-CoV-2 vaccines have shown very high effectiveness in real-world scenarios. However, there is compelling evidence for a fast-paced waning of immunity.
Tulio J. Lopera   +8 more
doaj   +1 more source

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