STUDIES ON THE HETEROLOGOUS IMMUNOGENICITY OF A METHANOL-INSOLUBLE FRACTION OF ATTENUATED TUBERCLE BACILLI (BCG) [PDF]
David Weiss+2 more
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Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon+25 more
wiley +1 more source
PREPARATION AND BIOLOGICAL PROPERTIES OF A CHEMICALLY MODIFIED ESCHERICHIA COLI ENDOTOXIN OF HIGH IMMUNOGENIC POTENCY AND LOW TOXICITY [PDF]
Hans Noll, Abraham I. Braude
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Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan+11 more
wiley +1 more source
Immunogenicity of Cell Walls from Various Mycobacteria Against Airborne Tuberculosis in Mice [PDF]
W Brehmer, R. L. Anacker, Edgar Ribi
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Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi+7 more
wiley +1 more source
A note on the immunogenicity of ultra-violet irradiated vaccinia virus in man [PDF]
C. Kaplan, D. McClean, L. Vallet
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A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang+16 more
wiley +1 more source
An mRNA-based seasonal influenza vaccine in adults: Results of two phase 3 randomized clinical trials and correlate of protection analysis of hemagglutination inhibition titers. [PDF]
Kandinov B+22 more
europepmc +1 more source
The immunogenicity of heat-inactivated vaccinia virus in rabbits [PDF]
C Madeley
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