Results 51 to 60 of about 844,089 (291)

Feline Immunoglobulins [PDF]

Infection and Immunity, 1974
Immunoglobulins (Ig) in feline sera and secretions were identified by immuno-electrophoresis and immunodiffusion with rabbit antisera prepared to feline IgG, IgA, IgM, and whole serum. Adult cat sera, colostral whey, postcolostral sera, tears, and nasal secretions contained IgG, IgA, and IgM.
R D, Schultz, F W, Scott, J R, Duncan, J H, Gillespie   +3 more
openaire   +2 more sources

Health-Related Quality of Life in Patients with CVID Under Different Schedules of Immunoglobulin Administration: Prospective Multicenter Study [PDF]

, 2019
We assessed the health-related quality of life (HRQoL) in CVID adults receiving different schedules of immunoglobulin replacement therapy (IgRT) by intravenous (IVIG), subcutaneous (SCIG), and facilitated (fSCIG) preparations.
Agostini, Carlo, Bonanni, Livia, Carrabba, Maria, Cinetto, Francesco, Crescenzi, Ludovica, Fabio, Giovanna, Farrugia, Albert, Milito, Cinzia, Neri, Raffaella, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Spadaro, Giuseppe, Tabolli, Stefano   +13 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

TNF-α x FcαRI bi-specific antibody potentiates neutrophil-mediated anti-tumor effects

Scientific Reports
Immunotherapy has emerged as a promising strategy against cancer, but many patients fail to achieve durable responses. Inefficiency of immunotherapy is often caused by the immunosuppressive tumor microenvironment.
D. Y. Gout, C. A. N. Sewnath, G. Duru, R. van der Mast, C. W. Tuk, A. E. H. Bentlage, M. Gruijs, G. Vidarsson, N. Heemskerk, M. van Egmond   +9 more
doaj   +1 more source

Transfer of passive immunity in dairy calves: the effectiveness of providing a supplementary colostrum meal in addition to nursing from the dam

Animal, 2019
Failed transfer of passive immunity (FTPI) in dairy calves – which is often due to the low amount of colostrum provided within a few hours after birth – remains a crucial issue.
I. Lora, F. Gottardo, L. Bonfanti, A.L. Stefani, E. Soranzo, B. Dall’Ava, K. Capello, M. Martini, A. Barberio   +8 more
doaj   +1 more source

Expression of the Thyroid Hormone Receptor Gene, erbAα, in B Lymphocytes: Alternative mRNA Processing is Independent of Differentiation but Correlates with Antisense RNA Levels [PDF]

, 1997
The erbAα gene encodes two α-thyroid hormone receptor isoforms, TRα1 and TRα2, which arise from alternatively processed mRNAs, erbAα1 (α1) and erb α2 (α2).
Hastings, Michelle Laura, Martincic, Kathlee, Milcarek, Christine, Munroe, Stephen H., Peterson, Martha L.   +4 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria

Nature Communications
Protective immunity to malaria depends on acquisition of parasite-specific antibodies, with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) being one of the most important target antigens.
Mary Lopez-Perez, Zakaria Seidu, Mads Delbo Larsen, Wenjun Wang, Jan Nouta, Manfred Wuhrer, Gestur Vidarsson, Michael F. Ofori, Lars Hviid   +8 more
doaj   +1 more source

Genetic associations of colostrum yield with antibody concentrations and gross composition for selective breeding in Italian Holsteins

Journal of Dairy Science
: The quality of bovine colostrum (BC), primarily determined by the concentration of IgG, is essential for the transfer of passive immunity and the development of the gastrointestinal tract in neonates.
Arianna Goi, Angela Costa, Mauro Penasa, Martino Cassandro, Maurizio Marusi, Raffaella Finocchiaro, Massimo De Marchi   +6 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source