Results 31 to 40 of about 666,636 (307)

Serum Free Light Chains in Common Variable Immunodeficiency Disorders: Role in Differential Diagnosis and Association With Clinical Phenotype

open access: yesFrontiers in Immunology, 2020
We report on an observational, multicenter study of 345 adult CVID patients, designed to assess the diagnostic value and the clinical association of serum free light chain (sFLC) pattern in Common Variable Immunodeficiency disorders (CVID).
Riccardo Scarpa   +22 more
doaj   +1 more source

Accurate Prediction and Key Feature Recognition of Immunoglobulin

open access: yesApplied Sciences, 2021
Immunoglobulin, which is also called an antibody, is a type of serum protein produced by B cells that can specifically bind to the corresponding antigen.
Yuxin Gong   +3 more
doaj   +1 more source

Intravenous immunoglobulin treatment in children with PANS/PANDAS conditions [PDF]

open access: yes, 2021
Key messages: PANS (Pediatric Acute onset Neuropsychiatric Syndrome)/PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections) is described as an abrupt, dramatic onset of obsessive-compulsive disorder (OCD) or ...
Grøvan, Anette Olsson   +1 more
core   +1 more source

Treatment of immunoglobulin-resistant kawasaki disease: a Bayesian network meta-analysis of different regimens

open access: yesFrontiers in Pediatrics, 2023
BackgroundThis study aimed to gather evidence from clinical trials on the efficacy and safety of the available treatments for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) in children.MethodsThis work adopted the Newcastle–Ottawa ...
Yan Pan, Qihong Fan, Luoyi Hu
doaj   +1 more source

Kappa Free Light Chains in the Context of Blood Contamination, and Other IgA- and IgM-Related Cerebrospinal Fluid Disease Pattern

open access: yesCells, 2021
In this retrospective, monocentric cohort study, we tested if an intrathecal free light chain kappa (FLC-k) synthesis reflects not only an IgG but also IgA and IgM synthesis.
Malte Johannes Hannich   +5 more
doaj   +1 more source

Effects of using different levels of dietary chitosan on some immune indices and antioxidant defense system in Vannamei shrimp, Litopenaeus vannamei [PDF]

open access: yesتغذیه آبزیان
Introduction: Aquaculture aims to provide stable environmental conditions for fish to be able to grow and protect it from stress and diseases. To guarantee a sustainable yield of fish species, well-balanced diets should be considered.
Saeed Dayani   +3 more
doaj   +1 more source

Identification of Glycoxidative Lesion in Isolated Low-Density Lipoproteins from Diabetes Mellitus Subjects

open access: yesLife, 2023
Methylglyoxal (MG) is a precursor for advanced glycation end-products (AGEs), which have a significant role in diabetes. The present study is designed to probe the immunological response of native and glycated low-density lipoprotein (LDL) in ...
Amjad R. Alyahyawi   +9 more
doaj   +1 more source

Single Domain Antibody Fragments as Drug Surrogates Targeting Protein–Protein Interactions inside Cells

open access: yesAntibodies, 2013
Many human diseases are caused by mutant or abnormal protein functions that are largely confined to the inside of cells, rather than being displayed on the abnormal cell surface. Furthermore, many of the functional consequences of aberrant proteins, such
Terence H. Rabbitts   +3 more
doaj   +1 more source

Immunoglobulin variable-region gene mutational lineage tree analysis: application to autoimmune diseases [PDF]

open access: yes, 2006
Lineage trees have frequently been drawn to illustrate diversification, via somatic hypermutation (SHM), of immunoglobulin variable-region (IGV) genes. In order to extract more information from IGV sequences, we developed a novel mathematical method for ...
Gitit Shahaf   +23 more
core   +1 more source

Fish Immunoglobulins [PDF]

open access: yesBiology, 2016
The B cell receptor and secreted antibody are at the nexus of humoral adaptive immunity. In this review, we summarize what is known of the immunoglobulin genes of jawed cartilaginous and bony fishes. We focus on what has been learned from genomic or cDNA sequence data, but where appropriate draw upon protein, immunization, affinity and structural ...
Sara Mashoof, Michael F. Criscitiello
openaire   +3 more sources

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