Results 21 to 30 of about 848,800 (312)

Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish

open access: yeseLife, 2022
Aging individuals exhibit a pervasive decline in adaptive immune function, with important implications for health and lifespan. Previous studies have found a pervasive loss of immune-repertoire diversity in human peripheral blood during aging; however ...
William John Bradshaw   +4 more
doaj   +1 more source

KIR2DL2/2DL3-E(35) alleles are functionally stronger than -Q(35) alleles. [PDF]

open access: yes, 2016
KIR2DL2 and KIR2DL3 segregate as alleles of a single locus in the centromeric motif of the killer cell immunoglobulin-like receptor (KIR) gene family. Although KIR2DL2/L3 polymorphism is known to be associated with many human diseases and is an important
Bao, Ju   +5 more
core   +1 more source

Serum Free Light Chains in Common Variable Immunodeficiency Disorders: Role in Differential Diagnosis and Association With Clinical Phenotype

open access: yesFrontiers in Immunology, 2020
We report on an observational, multicenter study of 345 adult CVID patients, designed to assess the diagnostic value and the clinical association of serum free light chain (sFLC) pattern in Common Variable Immunodeficiency disorders (CVID).
Riccardo Scarpa   +22 more
doaj   +1 more source

Accurate Prediction and Key Feature Recognition of Immunoglobulin

open access: yesApplied Sciences, 2021
Immunoglobulin, which is also called an antibody, is a type of serum protein produced by B cells that can specifically bind to the corresponding antigen.
Yuxin Gong   +3 more
doaj   +1 more source

Treatment of immunoglobulin-resistant kawasaki disease: a Bayesian network meta-analysis of different regimens

open access: yesFrontiers in Pediatrics, 2023
BackgroundThis study aimed to gather evidence from clinical trials on the efficacy and safety of the available treatments for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) in children.MethodsThis work adopted the Newcastle–Ottawa ...
Yan Pan, Qihong Fan, Luoyi Hu
doaj   +1 more source

Immunoglobulin therapy [PDF]

open access: yesClinical Medicine, 2016
Immunoglobulin is an expensive blood product of potentially limited supply used in a wide variety of medical conditions, across a number of specialties. Historically, immunoglobulin has been associated with transmission of blood borne infection (eg hepatitis C). Immunoglobulin use needs to be carefully considered, appropriately prescribed and recorded.
Sarah Louise, Johnston   +1 more
openaire   +2 more sources

Kappa Free Light Chains in the Context of Blood Contamination, and Other IgA- and IgM-Related Cerebrospinal Fluid Disease Pattern

open access: yesCells, 2021
In this retrospective, monocentric cohort study, we tested if an intrathecal free light chain kappa (FLC-k) synthesis reflects not only an IgG but also IgA and IgM synthesis.
Malte Johannes Hannich   +5 more
doaj   +1 more source

The immunoglobulin κ gene families of human and mouse: a cottage industry approach [PDF]

open access: yes, 2000
Some aspects of the work of our group on the human and mouse immunoglobulin κ genes are reviewed. The human κ locus contains a large duplication: a 600 kb C κ-proximal copy with 40 V κ genes is found in the close vicinity of a 440 kb C κ-distal copy with
Zachau, Hans G.
core   +1 more source

Effects of using different levels of dietary chitosan on some immune indices and antioxidant defense system in Vannamei shrimp, Litopenaeus vannamei [PDF]

open access: yesتغذیه آبزیان
Introduction: Aquaculture aims to provide stable environmental conditions for fish to be able to grow and protect it from stress and diseases. To guarantee a sustainable yield of fish species, well-balanced diets should be considered.
Saeed Dayani   +3 more
doaj   +1 more source

Identification of Glycoxidative Lesion in Isolated Low-Density Lipoproteins from Diabetes Mellitus Subjects

open access: yesLife, 2023
Methylglyoxal (MG) is a precursor for advanced glycation end-products (AGEs), which have a significant role in diabetes. The present study is designed to probe the immunological response of native and glycated low-density lipoprotein (LDL) in ...
Amjad R. Alyahyawi   +9 more
doaj   +1 more source

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