Results 51 to 60 of about 532,269 (266)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of Dairy Science: Enriching low- or moderate-quality maternal colostrum (MC) by directly adding dry commercial colostrum replacement (CR) powder into MC is convenient, but it is unknown whether this may increase osmolality of the CR-MC mixture to levels that could ...
W.A. Knauer +5 more
doaj +1 more source
Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age
Frontiers in Immunology, 2020 B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied.
Marie Ghraichy +18 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Biological topicals in ocular surface disorders
Indian Journal of OphthalmologyTopical biological agents represent a significant advancement in the treatment of ocular surface diseases, offering a regenerative and therapeutic approach beyond conventional therapies.
Sridevi Nair +2 more
doaj +1 more source
Phagocytosis: Our Current Understanding of a Universal Biological Process
Frontiers in Immunology, 2020 Phagocytosis is a cellular process for ingesting and eliminating particles larger than 0.5 μm in diameter, including microorganisms, foreign substances, and apoptotic cells.
Eileen Uribe-Querol, Carlos Rosales
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Biology, 2016 The B cell receptor and secreted antibody are at the nexus of humoral adaptive immunity. In this review, we summarize what is known of the immunoglobulin genes of jawed cartilaginous and bony fishes. We focus on what has been learned from genomic or cDNA sequence data, but where appropriate draw upon protein, immunization, affinity and structural ...
Sara Mashoof, Michael F. Criscitiello
openaire +3 more sources
Plasma cell myeloma in a 9‐year‐old male: Case report and literature review
Clinical Case ReportsKey Clinical Message Plasma cell myeloma is a rare entity in the pediatric population. The peak incidence is in the seventh decade, with less than 2% of cases occurring in patients under the age of 40.
Kato Ronald +2 more
doaj +1 more source
Atypical Kawasaki Disease Presenting as Intestinal Pseudo-obstruction
Journal of the Formosan Medical Association, 2006 Intestinal pseudo-obstruction in atypical Kawasaki disease (KD) is rare. A boy aged 2 years and 6 months presented with a 7-day history of fever, coffee-ground vomit, and abdominal pain.
Mao-Meng Tiao +3 more
doaj +1 more source