Results 51 to 60 of about 848,800 (312)

Allelic Variation in Protein Tyrosine Phosphatase Receptor Type-C in Cattle Influences Erythrocyte, Leukocyte and Humoral Responses to Infestation With the Cattle Tick Rhipicephalus australis

Frontiers in Immunology, 2021
The protein tyrosine phosphatase receptor type-C (PTPRC) gene encodes the common leukocyte antigen (CD45) receptor. CD45 affects cell adhesion, migration, cytokine signalling, cell development, and activation state.
Nicholas N. Jonsson, David K. Cox, Emily K. Piper, Emily F. Mantilla Valdivieso, Constantin Constantinoiu, Louise A. Jackson, Michael J. Stear, Elizabeth M. Ross, Ala E. Tabor   +8 more
doaj   +1 more source

Expression of the Thyroid Hormone Receptor Gene, erbAα, in B Lymphocytes: Alternative mRNA Processing is Independent of Differentiation but Correlates with Antisense RNA Levels [PDF]

, 1997
The erbAα gene encodes two α-thyroid hormone receptor isoforms, TRα1 and TRα2, which arise from alternatively processed mRNAs, erbAα1 (α1) and erb α2 (α2).
Hastings, Michelle Laura, Martincic, Kathlee, Milcarek, Christine, Munroe, Stephen H., Peterson, Martha L.   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Laboratory test results of serum and cerebrospinal fluid in patients with neurosyphilis and their diagnostic value

Pifu-xingbing zhenliaoxue zazhi
[Objective] To analyze the laboratory test results of serum and cerebrospinal fluid (CSF) in patients with neurosyphilis (NS) and explore the risk factors for the onset of NS and their diagnostic value. [Methods] A retrospective analysis was conducted on
GAO Pingping, ZHANG Xiaolong, SUN Zhe, ZHANG Ran, WANG Jing   +4 more
doaj   +1 more source

Stress as Trigger Factor of HSV-1 Reactivation Causing Recurrent Intraoral Herpes Mimicking HAEM: A Case Report

International Medical Case Reports Journal, 2022
Novia Tri Hasanah,1 Wahyu Hidayat2 1Oral Medicine Residency Program, Department of Oral Medicine, Universitas Padjadjaran, Bandung, Indonesia; 2Department of Oral Medicine, Universitas Padjadjaran, Bandung, IndonesiaCorrespondence: Novia Tri Hasanah ...
Hasanah NT, Hidayat W
doaj  

Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease

Journal of the Formosan Medical Association, 2016
Kawasaki disease (KD) is the most common pediatric vasculitis. The study aimed to identify the risk factors of intravenous immunoglobulin (IVIG) unresponsiveness from the initial clinical parameters of the Taiwanese KD patients.
Ming-Tai Lin, Chin-Hao Chang, Li-Chuan Sun, Hsin-Min Liu, Huei-Wen Chang, Chun-An Chen, Shuenn-Nan Chiu, Chun-Wei Lu, Luan-Yin Chang, Jou-Kou Wang, Mei-Hwan Wu   +10 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Controlled field study investigating effects of 2 methods of enriching moderate-quality maternal colostrum on transfer of passive immunity and well-being of neonatal dairy calves

Journal of Dairy Science
: Enriching low- or moderate-quality maternal colostrum (MC) by directly adding dry commercial colostrum replacement (CR) powder into MC is convenient, but it is unknown whether this may increase osmolality of the CR-MC mixture to levels that could ...
W.A. Knauer, M.A. Brown, E.M. Oosterheert, R. Schell, A. Geiger, S.M. Godden   +5 more
doaj   +1 more source

Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age

Frontiers in Immunology, 2020
B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied.
Marie Ghraichy, Marie Ghraichy, Jacob D. Galson, Jacob D. Galson, Aleksandr Kovaltsuk, Valentin von Niederhäusern, Valentin von Niederhäusern, Jana Pachlopnik Schmid, Jana Pachlopnik Schmid, Mike Recher, Annaïse J. Jauch, Enkelejda Miho, Enkelejda Miho, Enkelejda Miho, Dominic F. Kelly, Dominic F. Kelly, Charlotte M. Deane, Johannes Trück, Johannes Trück   +18 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source