Results 61 to 70 of about 1,199,652 (392)

Corticosterone selectively decreases humoral immunity in female eiders during incubation

, 2007
Immunity is hypothesized to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction.
Bourgeon, Sophie, Raclot, Thierry
core   +1 more source

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription [PDF]

, 1991
Virus-transformed pre-B cells undergo ordered immunoglobulin (Ig) gene rearrangements during culture. We devised a series of highly sensitive polymerase chain reaction assays for Ig gene rearrangement and unrearranged Ig gene segment transcription to ...
Baltimore, David, Corcoran, Lynn M., Schlissel, Mark S.   +2 more
core   +5 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Laboratory test results of serum and cerebrospinal fluid in patients with neurosyphilis and their diagnostic value

Pifu-xingbing zhenliaoxue zazhi
[Objective] To analyze the laboratory test results of serum and cerebrospinal fluid (CSF) in patients with neurosyphilis (NS) and explore the risk factors for the onset of NS and their diagnostic value. [Methods] A retrospective analysis was conducted on
GAO Pingping, ZHANG Xiaolong, SUN Zhe, ZHANG Ran, WANG Jing   +4 more
doaj   +1 more source

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma

Nature Communications, 2015
Multiple myeloma (MM) is characterized by an uninhibited, clonal growth of plasma cells. While first-degree relatives of patients with MM show an increased risk of MM, the genetic basis of inherited MM susceptibility is incompletely understood.
Bhairavi Swaminathan, G. Thorleifsson, Magnus Jöud, Mina Ali, E. Johnsson, Ram Ajore, P. Sulem, Britta Halvarsson, G. Eyjolfsson, V. Haraldsdóttir, C. Hultman, E. Ingelsson, S. Kristinsson, A. Kähler, S. Lenhoff, G. Másson, U. Mellqvist, R. Månsson, S. Nelander, I. Olafsson, Ólöf Sigurðardóttir, H. Steingrímsdóttir, A. Vangsted, U. Vogel, A. Waage, H. Nahi, D. Gudbjartsson, T. Rafnar, I. Turesson, U. Gullberg, K. Stefánsson, M. Hansson, U. Thorsteinsdóttir, B. Nilsson   +33 more
semanticscholar   +1 more source

KIR2DL2/2DL3-E(35) alleles are functionally stronger than -Q(35) alleles. [PDF]

, 2016
KIR2DL2 and KIR2DL3 segregate as alleles of a single locus in the centromeric motif of the killer cell immunoglobulin-like receptor (KIR) gene family. Although KIR2DL2/L3 polymorphism is known to be associated with many human diseases and is an important
Bao, Ju, Bari, Rafijul, Leung, Wing, Li, Ying, Thapa, Rajoo, Zheng, Jie   +5 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Stress as Trigger Factor of HSV-1 Reactivation Causing Recurrent Intraoral Herpes Mimicking HAEM: A Case Report

International Medical Case Reports Journal, 2022
Novia Tri Hasanah,1 Wahyu Hidayat2 1Oral Medicine Residency Program, Department of Oral Medicine, Universitas Padjadjaran, Bandung, Indonesia; 2Department of Oral Medicine, Universitas Padjadjaran, Bandung, IndonesiaCorrespondence: Novia Tri Hasanah ...
Hasanah NT, Hidayat W
doaj  

Risk factors and derived formosa score for intravenous immunoglobulin unresponsiveness in Taiwanese children with Kawasaki disease

Journal of the Formosan Medical Association, 2016
Kawasaki disease (KD) is the most common pediatric vasculitis. The study aimed to identify the risk factors of intravenous immunoglobulin (IVIG) unresponsiveness from the initial clinical parameters of the Taiwanese KD patients.
Ming-Tai Lin, Chin-Hao Chang, Li-Chuan Sun, Hsin-Min Liu, Huei-Wen Chang, Chun-An Chen, Shuenn-Nan Chiu, Chun-Wei Lu, Luan-Yin Chang, Jou-Kou Wang, Mei-Hwan Wu   +10 more
doaj   +1 more source

Allelic Variation in Protein Tyrosine Phosphatase Receptor Type-C in Cattle Influences Erythrocyte, Leukocyte and Humoral Responses to Infestation With the Cattle Tick Rhipicephalus australis

Frontiers in Immunology, 2021
The protein tyrosine phosphatase receptor type-C (PTPRC) gene encodes the common leukocyte antigen (CD45) receptor. CD45 affects cell adhesion, migration, cytokine signalling, cell development, and activation state.
Nicholas N. Jonsson, David K. Cox, Emily K. Piper, Emily F. Mantilla Valdivieso, Constantin Constantinoiu, Louise A. Jackson, Michael J. Stear, Elizabeth M. Ross, Ala E. Tabor   +8 more
doaj   +1 more source