Results 51 to 60 of about 120,903,364 (211)

Cidofovir and intravenous immunoglobulin for treatment of BK polyomarivus nephropathy [PDF]

, 2006
BK polyomavirus nephropathy (BKN) is an important cause of renal allograft dysfunction and loss. The mainstay of therapy is reduced immunosuppression, but definitive protocols for the diagnosis and management remain to be defined.
Mehrotra, MD, Anita, Dinavahi, MD, Rajani, Francos, MD, George C., Anita Mehrotra, Rajani Dinavahi, George Francos   +5 more
core   +1 more source

Identification of Potential Biomarkers in IgA Nephropathy and Membranous Nephropathy through miRNA-mRNA bioinformatics analysis

Journal of the Pakistan Medical Association
Objective: Immunoglobulin A nephropathy and membranous nephropathy are glomerulus disease. The current study was planned to understand the molecular mechanism of immunoglobulin A nephropathy and membranous nephropathy with discovery of key micro ...
Areeba Irfan, Zoha Adnan, Muhammad Ibrahim, Farrukh Jamil, Muhammad Asif Rasheed   +4 more
doaj   +1 more source

The Study of Angptl4-Modulated Podocyte Injury in IgA Nephropathy

Frontiers in Physiology, 2021
BackgroundIncreasing evidence shows that Angptl4 affects proteinuria in podocytes injured kidney disease, however, whether there is a relationship between Angptl4 and IgA nephropathy (IgAN) has not been studied yet.MethodsPlasma and urine samples were ...
Sha Jia, Sha Jia, Sha Jia, Sha Jia, Sha Jia, Sha Jia, Xiaofeng Peng, Xiaofeng Peng, Xiaofeng Peng, Xiaofeng Peng, Xiaofeng Peng, Ludan Liang, Ludan Liang, Ludan Liang, Ludan Liang, Ludan Liang, Ying Zhang, Ying Zhang, Ying Zhang, Ying Zhang, Ying Zhang, Meng Li, Meng Li, Meng Li, Meng Li, Meng Li, Qin Zhou, Qin Zhou, Qin Zhou, Qin Zhou, Qin Zhou, Xiujin Shen, Xiujin Shen, Xiujin Shen, Xiujin Shen, Xiujin Shen, Yucheng Wang, Yucheng Wang, Yucheng Wang, Yucheng Wang, Yucheng Wang, Cuili Wang, Cuili Wang, Cuili Wang, Cuili Wang, Cuili Wang, Shi Feng, Shi Feng, Shi Feng, Shi Feng, Shi Feng, Jianghua Chen, Jianghua Chen, Jianghua Chen, Jianghua Chen, Jianghua Chen, Pingping Ren, Pingping Ren, Pingping Ren, Pingping Ren, Pingping Ren, Hong Jiang, Hong Jiang, Hong Jiang, Hong Jiang, Hong Jiang   +65 more
doaj   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Toxoplasma gondii Infection After Kidney Transplantation: A Case Report and Literature Review

Organ Medicine, EarlyView.
Toxoplasma gondii infection after kidney transplantation is rare and presents with nonspecific clinical manifestations; however, the associated mortality rate is high. We discuss the relevant literature, clinical manifestations, therapeutic regimens, and prognoses of post‐transplantation toxoplasmosis.
Peng Zhang, Xingqiang Lai, Rongxin Chen, Li Li, Jiali Fang, Guanghui Li, Junjie Ma, Luhao Liu, Zheng Chen   +8 more
wiley   +1 more source

Current therapeutic management of diabetic nephropathy [PDF]

, 1994
Roughly 40% of all patients with insulin-dependent diabetes mellitus (IDDM) develop diabetic nephropathy with proteinuria, hypertension and a decrease in glomerular filtration rate 10 to 20 years after the onset of the disease, and 5 years later most ...
Kohler, S. M., Krämer, Bernhard K.
core   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Sibeprenlimab, which neutralizes A PRoliferation Inducing Ligand (APRIL), as a new approach to treating IgA nephropathy [PDF]

Introduction Immunoglobulin A (IgA) nephropathy is a common immune-mediated kidney disease leading to high blood pressure and may progress to kidney failure. None of the present treatments are disease-modifying or prolong life.
Doggrell, Sheila A
core   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Update on treatment of immunoglobulin A nephropathy [PDF]

Nephrology, 2018
ABSTRACTImmunoglobulin A nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and the most common cause of end‐stage renal disease in young adults. However, there are still no specific therapies capable of targeting key pathways involved in disease pathogenesis.
Yue-Miao, Zhang, Hong, Zhang
openaire   +2 more sources