Immunoglobulin E and systemic lupus erythematosus [PDF]
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by intense polyclonal production of autoantibodies and circulating immune complexes. Some reports have associated SLE with a Th2 immune response and allergy. In the present study 21 female patients with SLE were investigated for total IgE and IgE antibodies to dust house ...
Atta, A.M.+3 more
openaire +5 more sources
Kimura disease: A rare presentation in the rheumatology clinic
Kimura disease (KD) is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling in head and neck region, accompanied by regional lymphadenopathy and ...
Malay Kumar+4 more
doaj +1 more source
Avian Resistance to Campylobacter jejuni Colonization Is Associated with an Intestinal Immunogene Expression Signature Identified by mRNA Sequencing [PDF]
peer-reviewedThis research was funded by the The Irish Department of Agriculture and Food’s Food Institutional Research Measure (http://www.agriculture.gov.ie/ research/foodinstitutionalresearchmeasurefirm) – Grant No: 06_RDD_486.Campylobacter jejuni is
Allan, Brenda+8 more
core +3 more sources
A Fluorescent Biosensor Reveals Conformational Changes in Human Immunoglobulin E Fc
Background: Immunoglobulin E (IgE) antibodies play a role in allergic disease. Results: IgE has a bent conformation in solution that becomes more bent upon binding to the FcϵRI receptor but less bent upon binding the anti-IgE omalizumab.
J. Hunt+10 more
semanticscholar +1 more source
Evolution of antigen binding receptors [PDF]
This review addresses issues related to the evolution of the complex multigene families of antigen binding receptors that function in adaptive immunity.
Anderson, Michele K.+2 more
core +1 more source
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3 [PDF]
INTRODUCTION: Involution of the mammary gland is a complex process of controlled apoptosis and tissue remodelling. The aim of the project was to identify genes that are specifically involved in this process.
Bell, A.K.+9 more
core
Vogt-Koyanagi-Harada Syndrome in Two Patients with Immunoglobulin A Nephropathy [PDF]
We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-
Masuda, Ikuya+5 more
core +1 more source
Background Asthma affects 300 million individuals worldwide. It is a serious global health problem affecting all age groups. The significance of eosinophilic inflammation in asthma is well established.
Mohamed A Elmoniem+3 more
doaj +1 more source
Fatal infusion reactions to cetuximab: role of immunoglobulin e-mediated anaphylaxis.
report a fatal hypersensitivity reaction to cetuximab in a 63-year-old patient with metastatic colon cancer and outlined a 0.1% incidence of death in the literature. We greatly acknowledge the authors’ desire to communicate the risk of fatal anaphylactic
Y. Pointreau+4 more
semanticscholar +1 more source
IGHV mutational status of nodal marginal zone lymphoma by NGS reveals distinct pathogenic pathways with different prognostic implications [PDF]
The precise B cell of origin and molecular pathogenesis of nodal marginal zone lymphoma (NMZL) remain poorly defined. To date, due to the rarity of NMZL, the vast majority of already-published studies have been conducted on a limited number of samples ...
Amato, Teresa+15 more
core +2 more sources