Results 241 to 250 of about 616,488 (308)

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Prevalence of immunoglobulin E sensitization to various inhaled allergens among the residents of the Northern United Arab Emirates: Automated evaluation of a membrane-based test system. [PDF]

Saudi Med J
Yousif IO, Rahamathullah N, Khan NS, Mesbahuzzaman M, Abdulrazzaq M, AlObeidli FA, Kandakurti PK.   +6 more
europepmc   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Total Serum IgE in a Cohort of Children With Food Allergy. [PDF]

J Allergy Clin Immunol Pract
Assa'ad AH, Ding L, Duan Q, Mersha TB, Warren C, Bilaver L, Ullrich M, Wlodarski M, Jiang J, Choi JJ, Xie SS, Kulkarni A, Fox S, Nimmagadda S, Tobin MC, Mahdavinia M, Sharma H, Gupta RS.   +17 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Obstructive uropathy in STAT 3 hyper immunoglobulin E syndrome: A 5 year old Middle Eastern boy. [PDF]

Saudi Med J
Bukhari EM, Alsaidalani AA.
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Prevalence of Allergen-Specific IgE Positivity and Serum Immunoglobulin E Concentrations of Allergens in Dogs with Suspected Allergic Dermatitis Using the Multiple Allergen Simultaneous Test in South Korea. [PDF]

Vet Sci
Jang YS, Han JI, Lee ES, Cheon DS, Nam A, Hyun JE.   +5 more
europepmc   +1 more source

Association between allergen-specific immunoglobulin E sensitization, allergic rhinitis symptoms, and quality of life in school-aged children. [PDF]

Sci Rep
Watanabe D, Otawa S, Kushima M, Yui H, Shinohara R, Yamagata Z, Sakurai D, Miyake K, Yamanashi Adjunct Study of the Japan Environment and Children’s Study Group.   +8 more
europepmc   +1 more source

Prospective Study of Vitamin D Status and Risk of Developing Specific Immunoglobulin E During Mid-Childhood. [PDF]

Clin Exp Allergy
Doumat G, El Zein J, Mehta GD, Zhu Z, Qi YS, Espinola JA, Sullivan AF, Hasegawa K, Camargo CA.   +8 more
europepmc   +1 more source