Results 221 to 230 of about 31,425,815 (302)

"Allergolds": Gold Nanocluster-Based Bioconjugates of Food Allergens with Reduced Immunoglobulin E Binding. [PDF]

ACS Omega
Martinez-Macias V, Gabel SA, Bennett JC, Smith SA, Mueller GA, Hallett-Tapley GL, Foo ACY.   +6 more
europepmc   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Genetic predisposition for immunoglobulin E production explains atopic risk in children: Tohoku Medical Megabank cohort study. [PDF]

Am J Hum Genet
Sutoh Y, Hachiya T, Otsuka-Yamasaki Y, Komaki S, Minabe S, Ohmomo H, Tanno K, Hozawa A, Nakaya N, Noda A, Orui M, Ishikuro M, Obara T, Kuriyama S, Sasaki M, Shimizu A.   +15 more
europepmc   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Graphene Aerogels With Spherical Pore Structure for Broad Frequency Regulation and Enhanced Low‐Frequency Response

Advanced Science, EarlyView.
A graphene aerogel with a spherical‐pore structure is constructed via microbubble templating. This unique architecture suppresses strain‐induced percolation of conductive networks, enabling dynamic frequency tuning. It also delivers enhanced low‐frequency absorption with an effective absorption bandwidth of 2.56 GHz, covering 91% of the low‐frequency ...
Liang Li, Jiale Yan, Gengping Wan, Changlong Du, Yubing Lv, Yongzhu Yan, Zhaoyang Li, Guizhen Wang   +7 more
wiley   +1 more source

Total immunoglobulin E levels in induced sputum reflect asthma control status. [PDF]

Clin Transl Allergy
Chen W, Liu X, Yao X, Hao Y, Zhou Z, Wang C, Wang M, Zhang L.   +7 more
europepmc   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source

Association between serum alder-specific immunoglobulin E positivity and seasonal onset of eosinophilic esophagitis. [PDF]

JGH Open
Watanabe A, Tanaka F, Sawada A, Nishida Y, Maruyama H, Ominami M, Otani K, Fukunaga S, Hosomi S, Fujiwara Y.   +9 more
europepmc   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

Advanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao, Wei Li, Zhencan Lin, Zengfa Deng, Ming Li, Zongrui Jiang, Changzhao Li, Dianbo Long, Yan Kang   +8 more
wiley   +1 more source

Innate lymphoid cells in immunoglobulin E-mediated food allergy. [PDF]

Curr Opin Allergy Clin Immunol
Ilangovan J, Neves JF, Santos AF.
europepmc   +1 more source