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Immunoglobulin E in aqueous humour

Experimental Eye Research, 1985
The level of immunoglobulin E (IgE) was determined in the aqueous humour (AH) and serum by particle counting immunoassay (limit of sensitivity: 0.2 IU ml-1). This level in the AH was below 0.75 IU ml-1 in case of senile cataract (n = 22) and ranged from this assumed normal value to 550 IU ml-1 in case of uveitis (n = 37), Fuchs' cyclitis (n = 11 ...
J P, Dernouchamps   +3 more
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Role of immunoglobulin E and immunoglobulin E receptors in bronchial asthma

Journal of Allergy and Clinical Immunology, 1981
The molecular and cellular events involved in the immediate hypersensitivity response, illustrated in Fig. 1, have received increasing attention in recent yeass. l* 2 Not only is this response the basis for allergic diseases but also it provides a relatively simple model for immunologic activation of specific cells, which may be applicable to other ...
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Immunoglobulin E in Renal Disease

Nephron, 1976
Samples of renal tissue from 373 patients were examined for the presence of immunoglobulin E (IgE) by immunofluorescent techniques. Only trace to ++ amounts ( on a scale of ++++) were found in 20 patients: 4/9 with post-streptococcal acute glomerulonephritis (GN), 5/30 with GN associated with systemic lupus erythematosus, 3/20 with membranous GN, 1/4 ...
M R, Robertson   +3 more
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Immunoglobulin E and bullous pemphigoid

European Journal of Dermatology, 2018
Clinical features and histological findings in bullous pemphigoid (BP) suggest a Th2-oriented inflammatory reaction, especially in the early stages of the disease. Elevated total serum IgE levels, blood eosinophilia, and elevated serum levels of different soluble inflammatory Th2 response mediators have been described in large cohorts of patients with ...
Cozzani, Emanuele   +3 more
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Immunoglobulin E Response during Measles

International Archives of Allergy and Immunology, 1984
Serum IgE levels were determined in 41 patients with measles infection. 23 patients (56%) had an increased level (> 20%) during the acute phase of the disease in comparison with the recovery phase. 14 showed no change, and decreased levels were observed in 4 patients only.
M, Shalit   +4 more
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Immunoglobulin E in Nigerian Onchocerciasis

The American Journal of Tropical Medicine and Hygiene, 1977
Total serum IgE was measured by radioimmunoassay in 58 adult Nigerian patients with untreated onchocerciasis. Levels in excess of 244.9 IU/ml, the mean level of the healthy Nigerian control subjects tested, were found in 86% of the patients. The levels were comparable to IgE levels found in 15 atopic Nigerian patients from the same residential area ...
A O, Somorin, D C, Heiner, R E, Ajugwo
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Immunoglobulin E in the Monkey

The Journal of Immunology, 1969
Abstract An immunoglobulin reacting with anti-human γE antibodies was detected in the sera of monkeys immunized with Ascaris antigen or infested with parasitic mites. The monkey protein gave a precipitin band with antiserum specific for the Fc portion of human γE, but failed to react with any of the antisera specific for the other human ...
K, Ishizaka, T, Ishizaka, T, Tada
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Immunoglobulin E and its regulators

Current Opinion in Allergy and Clinical Immunology, 2001
Novel paradigms are emerging in the field of IgE regulation. Gene-environment interactions are increasingly considered to be major determinants of the type and amplitude of allergen-induced antibody responses. At the molecular level, the mechanistic connection between transcription and switching has been strengthened by the recent discovery that class ...
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The discovery of immunoglobulin E

Immunology Letters, 2016
The discovery of immunoglobulin E (IgE) was a breakthrough in the field of allergy and immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy. The first clue to the existence of a substance responsible for hypersensitivity
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Immunoglobulin E (Reagin) and Allergy

Nature, 1971
A tissue-sensitizing factor found in the sera of allergic subjects has been identified as a unique immunoglobulin, IgE. Investigations of its mode of action could lead to the development of new forms of treatment.
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