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Immunoglobulin E and bullous pemphigoid
European Journal of Dermatology, 2018Clinical features and histological findings in bullous pemphigoid (BP) suggest a Th2-oriented inflammatory reaction, especially in the early stages of the disease. Elevated total serum IgE levels, blood eosinophilia, and elevated serum levels of different soluble inflammatory Th2 response mediators have been described in large cohorts of patients with ...
Cozzani, Emanuele +3 more
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Immunoglobulin E Response during Measles
International Archives of Allergy and Immunology, 1984Serum IgE levels were determined in 41 patients with measles infection. 23 patients (56%) had an increased level (> 20%) during the acute phase of the disease in comparison with the recovery phase. 14 showed no change, and decreased levels were observed in 4 patients only.
M, Shalit +4 more
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Immunoglobulin E in Nigerian Onchocerciasis
The American Journal of Tropical Medicine and Hygiene, 1977Total serum IgE was measured by radioimmunoassay in 58 adult Nigerian patients with untreated onchocerciasis. Levels in excess of 244.9 IU/ml, the mean level of the healthy Nigerian control subjects tested, were found in 86% of the patients. The levels were comparable to IgE levels found in 15 atopic Nigerian patients from the same residential area ...
A O, Somorin, D C, Heiner, R E, Ajugwo
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Immunoglobulin E in the Monkey
The Journal of Immunology, 1969Abstract An immunoglobulin reacting with anti-human γE antibodies was detected in the sera of monkeys immunized with Ascaris antigen or infested with parasitic mites. The monkey protein gave a precipitin band with antiserum specific for the Fc portion of human γE, but failed to react with any of the antisera specific for the other human ...
K, Ishizaka, T, Ishizaka, T, Tada
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Immunoglobulin E and its regulators
Current Opinion in Allergy and Clinical Immunology, 2001Novel paradigms are emerging in the field of IgE regulation. Gene-environment interactions are increasingly considered to be major determinants of the type and amplitude of allergen-induced antibody responses. At the molecular level, the mechanistic connection between transcription and switching has been strengthened by the recent discovery that class ...
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The discovery of immunoglobulin E
Immunology Letters, 2016The discovery of immunoglobulin E (IgE) was a breakthrough in the field of allergy and immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy. The first clue to the existence of a substance responsible for hypersensitivity
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Immunoglobulin E (Reagin) and Allergy
Nature, 1971A tissue-sensitizing factor found in the sera of allergic subjects has been identified as a unique immunoglobulin, IgE. Investigations of its mode of action could lead to the development of new forms of treatment.
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