Results 51 to 60 of about 19,118,362 (293)
Oral Manifestations of Job’s Syndrome in a Paediatric Dental Patient – A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2016 Job’s syndrome or Hyperimmunoglobulin E Syndrome (HIES) is a rare primary immunodeficiency with marked increase in serum immunoglobulin E (IgE) levels and eczematous dermatitis.
Jeswin James +2 more
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Immunoglobulin E, Interleukin-18 and Interleukin-12 in Patients with Atopic Dermatitis: Correlation with Disease Activity [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disorder. Immunological/inflammatory reactions are reported to play a role in AD but their role in disease activity has not been fully investigated. This study was done to investigate
Khaled Zedan +6 more
doaj +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Omalizumab, an anti-immunoglobulin E antibody: state of the art
Drug Design, Development and Therapy, 2014 A large number of trials show that the anti-immunoglobulin (Ig) E antibody omalizumab is very effective in patients with severe allergic asthma. This is acknowledged in consensus documents.
C. Incorvaia +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Idiopathic Anaphylaxis: Case Report
İstanbul Medical Journal, 2020 Anaphylaxis is a rapidly progressive and fatal type I hypersensitivity reaction. Food, venom and drugs are the most frequent triggers of anaphylaxis. Idiopathic anaphylaxis is identified when other causes are excluded, and there is no specific trigger. A
Öner Özdemir
doaj +1 more source
Immunoglobulin E plays an immunoregulatory role in lupus
Journal of Experimental Medicine, 2014 Dema et al. show evidence that deficiency of IgE delays lupuslike disease development and severity, as demonstrated by reduced autoantibody production and amelioration of organ pathologies.
B. Dema +16 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk +3 more
wiley +1 more source
Kimura's disease: A challenge to the cytologist
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2021 Kimura's disease is a rare idiopathic chronic inflammatory disease which usually presents as deep-seated subcutaneous swelling in the head and neck region.
Indranil Chakrabarti
doaj +1 more source