Results 61 to 70 of about 19,499,044 (379)
Immunoglobulin E in health and disease [PDF]
Asia Pacific Allergy, 2011 The discovery of immunoglobulin E (IgE) was a breakthrough in the field of Allergy and Immunology. Our understanding of mechanisms of allergic reactions and the role of IgE in these disorders has paralleled to the discovery of treatment modalities for patients with allergy.
openaire +3 more sources
Journal of Asthma and Allergy, 2021 Yusi Li,1,* Haisheng Hu,2,* Teng Zhang,1,* Guoliang Wang,1 Huimin Huang,2 Peiyan Zheng,2 Baoqing Sun,2 Xiaohua Douglas Zhang1 1Faculty of Health Sciences, University of Macau, Taipa, Macau, China; 2Department of Allergy and Clinical ...
Li Y +7 more
doaj
An Epigenome-Wide Association Study of Total Serum Immunoglobulin E Concentration
Nature, 2014 Immunoglobulin E (IgE) is a central mediator of allergic (atopic) inflammation. Therapies directed against IgE can alleviate hay fever and allergic asthma.
L. Liang +17 more
semanticscholar +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Egyptian Journal of Chest Disease and Tuberculosis, 2020 Background Laser acupuncture therapy has bioexcitation, tissue regenerative, antimicrobial, anti-inflammatory, and analgesic properties. Its impacts on pulmonary insults have offered gas exchange, ventilatory function, and immunity reinforcement ...
Rana H El-Helbawy +3 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2022 Background and Objective: Asthma is a chronic airway disorder with a rising prevalence. Dietary factors, antioxidant indicators and vitamin D deficiency are associated with the disease.
Sayyed Gholamreza Mortazavi Moghaddam +2 more
doaj
IgE multiple myeloma: detection and follow-up
Advances in Laboratory Medicine, 2021 We report a new case of immunoglobulin E multiple myeloma (IgE), a very rare isotype that accounts for
Nafría Jiménez Beatriz +1 more
doaj +1 more source
Molecular mimicry, genetic homology, and gene sharing proteomic “molecular fingerprints” using an EBV (Epstein-Barr virus)-derived microarray as a potential diagnostic method in autoimmune disease [PDF]
, 2018 EBV (Epstein-Barr Virus) and other human DNA viruses are associated with autoimmune syndromes in epidemiologic studies. In this work, immunoglobulin G response to EBV-encoded proteins which share regions with human immune response proteins from the human
Alessandra Farina, Giuseppina +2 more
core +1 more source