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The binding of protein A of immunoglobulin G and of Fab and Fc fragments.

Acta pathologica et microbiologica Scandinavica. Section C, Immunology, 1979
Results are presented to show that protein A (pA) may fix to the Fab region of IgG outside the antigen binding site. Thus, pA-reactive Fab fragments were isolated both from specific anti-egg albumin and specific anti-measles virus antibodies. A probable significance of this Fab reactivity in the precipitation reaction between IgG and pA is discussed ...
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