Results 41 to 50 of about 50,813 (225)
Cell-Free Synthesis Meets Antibody Production: A Review
Antibodies, 2015 Engineered antibodies are key players in therapy, diagnostics and research. In addition to full size immunoglobulin gamma (IgG) molecules, smaller formats of recombinant antibodies, such as single-chain variable fragments (scFv) and antigen binding ...
Marlitt Stech, Stefan Kubick
doaj +1 more source
Xenoantisera against a murine T cell tumor product cross-react with immunoglobulin Fab determinants.
Journal of Immunology, 1983 Some murine monoclonal T lymphoma cells express a surface component that reacts with chicken antisera produced against the Fab fragment of normal mouse IgG.
A. M. Mackel +4 more
semanticscholar +1 more source
mAbs, 2022 Although several antibody fragments and antibody fragment-fusion proteins produced in Escherichia coli (E. coli) are approved as therapeutics for various human diseases, a full-length monoclonal or a bispecific antibody produced in E.
Md Harunur Rashid
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Modelling Bi-specific Antibodies in Aqueous Solution [PDF]
arXiv, 2023 This study presents theoretical results for physico-chemical properties of system of molecules modeling bi-specific antibodies, such as, dual-variable-domain monoclonal antibodies (DVD-Ig) and Fabs-In-Tandem Immunoglobulin (FIT-Ig). These molecules are representatives of the engineered proteins that combine the function and specificity of two ...
arxiv
Bioinformatics and Biology Insights, 2021 Lung cancer is one of the leading causes of cancer-related deaths in the world among both men and women. Several studies in the literature report that overexpression and mutation of the epidermal growth factor receptor (EGFR) are implicated in the ...
Yurika Sastyarina +7 more
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Fab Four self-interaction in quantum regime [PDF]
Arbuzov, A.B. & Latosh, B.N. Eur. Phys. J. C (2017) 77: 702, 2017 Quantum behavior of the John Lagrangian from the Fab Four class of Covariant Galileons is stud- ied. We consider one-loop corrections to the John interaction due to cubic scalar field interactions. Counter Terms are calculated, one of them belongs to the Fab Four class, the other one to Covariant Galileons. The role of quantum corrections in context of
arxiv +1 more source
Virology Journal, 2018 Background The highly pathogenic avian influenza viruses of the H5 subtype, such as the H5N1 viral strains or the novel H5N8 and H5N2 reassortants, are of both veterinary and public health concern worldwide. To combat these viruses, monoclonal antibodies
Violetta Sączyńska +7 more
doaj +1 more source
Abstract P-45: Structural Studies of Multispecific Antibody/Antigen Complexes by Cryo-EM [PDF]
International Journal of Biomedicine, 2019 Background: Multispecific antibodies are artificially engineered molecules designed to bind simultaneously to several (different) antigens. Potential advantages of generating viable multispecific antibodies include the identification of malignant cells ...
David Fernandez-Martinez +3 more
doaj +1 more source
Direct IgG epitope mapping on bacterial AB toxins by cryo-EM
STAR Protocols, 2021 Summary: This cryo-EM protocol was used to determine the B cell epitope map on the CdtB subunit of typhoid toxin, an A2B5 toxin secreted by Salmonella Typhi during infection.
Tri Nguyen, Jeongmin Song
doaj
Fast Approximate Bayesian Contextual Cold Start Learning (FAB-COST) [PDF]
, 2020 Cold-start is a notoriously difficult problem which can occur in recommendation systems, and arises when there is insufficient information to draw inferences for users or items. To address this challenge, a contextual bandit algorithm -- the Fast Approximate Bayesian Contextual Cold Start Learning algorithm (FAB-COST) -- is proposed, which is designed ...
arxiv +1 more source