Results 41 to 50 of about 24,729 (207)

Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species [PDF]

, 2020
BACKGROUND: Flow cytometry is a powerful tool for the multiparameter analysis of leukocyte subsets on the single cell level. Recent advances have greatly increased the number of fluorochrome-labeled antibodies in flow cytometry.
Debes, Gudrun F., Hunka, Julia, Riley, John T   +2 more
core   +1 more source

Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]

, 1991
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte, Schwirzke, Marina, Weidle, Ulrich H., Weiss, Elisabeth H., Weissenhorn, Winfried   +4 more
core   +1 more source

Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor

Journal of Translational Medicine, 2019
Background Neuropsychiatric manifestations are frequent in patients with systemic lupus erythematosus (SLE), yet the etiology and pathogenesis of brain damage in SLE remains unclear.
Chunshu Yang, Xiaoyu Hou, Qianhui Feng, Yingzhuo Li, Xuejiao Wang, Ling Qin, Pingting Yang   +6 more
doaj   +1 more source

Few and Far Between: How HIV May Be Evading Antibody Avidity [PDF]

, 2010
No ...
Bjorkman, Pamela J., Klein, Joshua S.
core   +3 more sources

Characterization of egg yolk immunoglobulin (IgY) against enterotoxigenic Escherichia coli and evaluation of its effects on bovine intestinal cells [PDF]

, 2013
Escherichia coli (ETEC) infection is common in calves. Egg yolk antibodies (IgY) have been used to treat gastrointestinal infectious diseases. This study aimed to characterize IgY against bovine ETEC and to evaluate its effects on bovine intestinal cell ...
Alustiza, Fabrisio Eduardo, Bellingeri, Romina Valeria, Busso, Lucila, Grosso, Maria Carolina, Molinero, Daniela Paola, Motta, Carlos, Picco, Natalia Yanina, Vivas, Adriana Beatriz   +7 more
core   +1 more source

Protein L: a novel reagent for the detection of Chimeric Antigen Receptor (CAR) expression by flow cytometry

Journal of Translational Medicine, 2012
Background There has been significant progress in the last two decades on the design of chimeric antigen receptors (CAR) for adoptive immunotherapy targeting tumor-associated antigens.
Zheng Zhili, Chinnasamy Nachimuthu, Morgan Richard A   +2 more
doaj   +1 more source

Structural features of human immunoglobulin G that determine isotype-specific differences in complement activation. [PDF]

, 1993
Although very similar in sequence, the four subclasses of human immunoglobulin G (IgG) differ markedly in their ability to activate complement. Glu318-Lys320-Lys322 has been identified as a key binding motif for the first component of complement, C1q ...
Morrison, SL, Smith, RI, Tao, MH
core  

The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole [PDF]

, 2003
We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells.
Denecke, J. (Jurgen), Frigerio, Lorenzo, Hadlington, Jane L., Ma, Julian K.-C., Nuttall, James, Santoro, Aniello, Vitale, A. (Alessandro)   +6 more
core   +2 more sources

In silico antibody engineering for SARS-CoV-2 detection

Computational and Structural Biotechnology Journal, 2021
Engineered immunoglobulin-G molecules (IgGs) are of wide interest for the development of detection elements in protein-based biosensors with clinical applications.
Didac Martí, Eduard Martín-Martínez, Juan Torras, Oscar Bertran, Pau Turon, Carlos Alemán   +5 more
doaj  

Junctional Bradycardia as Early Sign of Digoxin Toxicity in a Premature Infant with Congestive Heart Failure due to a Left to Right Shunt

American Journal of Perinatology Reports, 2016
Introduction Congestive heart failure due to left to right cardiac shunt is usually managed medically with diuretics, angiotensin converting enzyme inhibitors, and, in some cases, with the addition of digoxin.
Soham Dasgupta, Ashraf M. Aly, Sunil K. Jain   +2 more
doaj   +1 more source