Results 181 to 190 of about 76,339 (318)

Clinical implications of imlifidase interference in antibody screening and transfusion management

open access: yesTransfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani   +2 more
wiley   +1 more source

Fc-Engineering Improves PET Imaging of Anti-Mesothelin VH-Fc across Multiple Tumor Mouse Models and Reveals Sex-Specific Renal Clearance. [PDF]

open access: yesBioconjug Chem
Bhise A   +8 more
europepmc   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

open access: yesTransfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike   +33 more
wiley   +1 more source

Widespread Fab-arm exchange affects all endogenous serum IgG4. [PDF]

open access: yesNat Commun
Wollenweber L   +4 more
europepmc   +1 more source

IgG4 anti‐CD47: Erythrophagocytosis and potential transfusion complications

open access: yesTransfusion, EarlyView.
Abstract Background IgG4 monoclonal anti‐CD47 for cancer immunotherapy resulted in anemia necessitating red cell (RBC) transfusions. Although the antibody readily binds to CD47 on RBCs, the mechanism underlying the anemia associated with IgG4 is poorly understood.
Kayluz Frias Boligan   +7 more
wiley   +1 more source

The Amino Acid Sequence of the Fc Fragment of Rabbit Immunoglobulin G

open access: yesJournal of Biological Chemistry, 1968
R Delaney, R L Hill
openaire   +2 more sources

Circulating tumor DNA determinants of response and outcome in relapsed/refractory mantle cell lymphoma. [PDF]

open access: yesBlood Adv
Meriranta L   +14 more
europepmc   +1 more source

The Role of Gene Flow in the Diversification of the Monkey Treefrog Complex Across the South American Dry Diagonal

open access: yesZoologica Scripta, EarlyView.
ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi   +10 more
wiley   +1 more source

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