Mechanistic Insights and Advances of Bispecific T Cell Engaging Antibodies Therapy in Multiple Myeloma. [PDF]
Tang TF +4 more
europepmc +1 more source
Clinical implications of imlifidase interference in antibody screening and transfusion management
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani +2 more
wiley +1 more source
Fc-Engineering Improves PET Imaging of Anti-Mesothelin VH-Fc across Multiple Tumor Mouse Models and Reveals Sex-Specific Renal Clearance. [PDF]
Bhise A +8 more
europepmc +1 more source
Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike +33 more
wiley +1 more source
Widespread Fab-arm exchange affects all endogenous serum IgG4. [PDF]
Wollenweber L +4 more
europepmc +1 more source
IgG4 anti‐CD47: Erythrophagocytosis and potential transfusion complications
Abstract Background IgG4 monoclonal anti‐CD47 for cancer immunotherapy resulted in anemia necessitating red cell (RBC) transfusions. Although the antibody readily binds to CD47 on RBCs, the mechanism underlying the anemia associated with IgG4 is poorly understood.
Kayluz Frias Boligan +7 more
wiley +1 more source
The Amino Acid Sequence of the Fc Fragment of Rabbit Immunoglobulin G
R Delaney, R L Hill
openaire +2 more sources
Circulating tumor DNA determinants of response and outcome in relapsed/refractory mantle cell lymphoma. [PDF]
Meriranta L +14 more
europepmc +1 more source
Atypical marginal zone hyperplasia of mucosa-associated lymphoid tissue: a reactive condition of childhood showing immunoglobulin lambda light-chain restriction [PDF]
Attygalle, AD +8 more
core +1 more source
ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi +10 more
wiley +1 more source

