722. Immunoglobulin Fc Fragment Tagging Enhances HBV Ag Specific T Cell Immune Responses in Mice Induced by Recombinant Lentivector Immunization [PDF]
, 2008 openalex +1 more source
Immunoglobulin Fc fragment tagging allows strong activation of endogenous CD4 T cells to re-shape the tumor milieu and enhance the antitumor effect of lentivector immunization (162.4) [PDF]
, 2012 Yukai He +5 more
openalex +1 more source
Characterisation of a new molecule based on two E2 sequences from bovine viral diarrhoea-mucosal disease virus fused to the human immunoglobulin Fc fragment [PDF]
, 2021 A. González +7 more
openalex +1 more source
Orphan designation: Glucagon analogue linked to a human immunoglobulin Fc fragment, Treatment of congenital hyperinsulinism [PDF]
, 2019 openalex +1 more source
Mass Spectrometry Reviews, EarlyView.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
Antibody‐Nanoparticle Conjugates in Therapy: Combining the Best of Two Worlds
Small, EarlyView.Antibody‐nanomaterial conjugates (ANCs) are an emerging therapeutic class combining the precise targeting specificity of antibodies with the versatility and functionality of nanomaterials. This review summarizes ANC design, synthesis, and potential therapeutic applications in this rapidly advancing field.
Aniruddha Adhikari, Irene A. Chen
wiley +1 more source
Small Science, EarlyView.In this study, a proof of concept is presented using an extended‐gate field‐effect‐transistor biosensing platform for monitoring immunotherapeutic drugs in vivo. Using varying sizes of immunotherapeutic drugs, the biosensor surpasses the sensitivity of standard methods, reducing the need for radioactive labeling in real‐time sensing.
Trang‐Anh Nguyen‐Le +8 more
wiley +1 more source
Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG1
Allergy, EarlyView.Sequential switching through IgG1 is not required to produce IgE with sufficient allergen‐binding affinity to cause anaphylaxis against food allergens. Sequential switching through IgG1 does not confer a competitive advantage to become an IgE‐expressing cell.
Joshua F. E. Koenig +11 more
wiley +1 more source
Determination of Physicochemical Properties of Human Immunoglobulin G- Fc Fragment by Bioinformatic [PDF]
, 2021 Soheyla Rohani, Fatemeh Hajighasemi
openalex +1 more source
CYP24A1 Binding to FUS Maintains Tumor Properties by Regulating the miR‐200c/ZEB1/EMT Axis
Cancer Science, EarlyView.The active vitamin D‐degrading enzyme (CYP24A1) is a potential oncogene in ovarian and lung cancer. Mechanically, 87–297 amino acid motif of CYP24A1 bound specifically to FUS protein, consequentially reducing FUS affinity for miR‐200c. A reduction in miR‐200c levels resulted in a significant activation of its target gene ZEB1, thereby facilitating the ...
Ping Wang +8 more
wiley +1 more source