Results 1 to 10 of about 116,527 (269)

Immunoglobulin heavy chain exclusion in the shark. [PDF]

open access: yesPLoS Biology, 2008
The adaptive immune system depends on specific antigen receptors, immunoglobulins (Ig) in B lymphocytes and T cell receptors (TCR) in T lymphocytes.
Karolina Malecek   +6 more
doaj   +5 more sources

Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age [PDF]

open access: yesFrontiers in Immunology, 2020
B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied.
Marie Ghraichy   +18 more
doaj   +5 more sources

Immunoglobulin heavy chains in medaka (Oryzias latipes) [PDF]

open access: yesBMC Evolutionary Biology, 2011
Abstract Background Bony fish present an immunological system, which evolved independently from those of animals that migrated to land 400 million years ago. The publication of whole genome sequences and the availability of several cDNA libraries for medaka (Oryzias latipes) permitted us to perform a thorough analysis
Magadán-Mompó, S. (Susana)   +2 more
openaire   +9 more sources

Disseminated Intravascular Coagulation Associated with Large Deletion of Immunoglobulin Heavy Chain

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2021
Although the majority of monogenic defects underlying primary immunodeficiency are microlesions, large lesions like large deletions are rare and constitute less than 10% of these patients.
Abbas Khalili   +4 more
doaj   +1 more source

Monoclonal gammopathy of renal significance: Spectrum of diseases and approach to a case

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2021
The occurrence of kidney diseases associated with a monoclonal gammopathy in the absence of symptomatic multiple myeloma is increasingly recognized. When the kidney is involved, the monoclonal etiology of these diseases results in clinical and laboratory
Rohit Tewari   +5 more
doaj   +1 more source

Mu heavy chain disease with MYD88 L265P mutation: an unusual manifestation of lymphoplasmacytic lymphoma

open access: yesDiagnostic Pathology, 2022
Background Mu heavy chain disease is a rare lymphoid neoplasm characterized by vacuolated bone marrow plasma cells and secretion of defective mu immunoglobulin heavy chains. The biological basis of mu heavy chain disease is poorly understood.
Vandana Baloda   +9 more
doaj   +1 more source

Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch. [PDF]

open access: yesPLoS ONE, 2017
Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu.
Binyue Han   +5 more
doaj   +1 more source

Gamma heavy chain disease associated with T-cell large granular lymphocyte lymphoproliferative disorder: case report and literature review.

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2023
Heavy chain diseases are rare B-cell neoplasms consisting of the production of a monoclonal immunoglobulin composed of the only heavy chain without corresponding light chains.
Maria Laura Bisegna   +5 more
doaj   +1 more source

Immunoglobulin heavy-chain-associated amyloidosis. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1990
Immunoglobulin- or multiple myeloma-associated amyloidosis has been distinguished by the tissue deposition of Congophilic, fibrillar protein consisting of light chains or light-chain fragments (AL amyloidosis). We now report the isolation and characterization of another form of immunoglobulin-associated amyloid obtained from a patient who had extensive
Alan Solomon   +2 more
openaire   +3 more sources

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