Results 11 to 20 of about 175,593 (310)

Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age [PDF]

open access: yesFrontiers in Immunology, 2020
B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied.
Marie Ghraichy   +18 more
doaj   +5 more sources

Immunoglobulin heavy chains in medaka (Oryzias latipes) [PDF]

open access: yesBMC Evolutionary Biology, 2011
Abstract Background Bony fish present an immunological system, which evolved independently from those of animals that migrated to land 400 million years ago. The publication of whole genome sequences and the availability of several cDNA libraries for medaka (Oryzias latipes) permitted us to perform a thorough analysis
Magadán-Mompó, S. (Susana)   +2 more
openaire   +9 more sources

Immunoglobulin heavy-chain-associated amyloidosis. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1990
Immunoglobulin- or multiple myeloma-associated amyloidosis has been distinguished by the tissue deposition of Congophilic, fibrillar protein consisting of light chains or light-chain fragments (AL amyloidosis). We now report the isolation and characterization of another form of immunoglobulin-associated amyloid obtained from a patient who had extensive
Alan Solomon   +2 more
openaire   +3 more sources

Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus. [PDF]

open access: yesPLoS ONE, 2014
Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative ...
Jenni Liljavirta   +4 more
doaj   +1 more source

Spin chain on a metallic surface: Dissipation-induced order vs. Kondo entanglement [PDF]

open access: yesPhys. Rev. B 106, L161103 (2022), 2022
We explore the physics of a spin-1/2 Heisenberg chain with Kondo interaction, $J_k$, to a two-dimensional electron gas. At weak $J_k$ the problem maps onto a Heisenberg chain locally coupled to a dissipative Ohmic bath. At the decoupled fixed point, the dissipation is a marginally relevant perturbation and drives long-range antiferromagnetic order ...
arxiv   +1 more source

Immunoglobulin heavy chain gene rearrangement in heavy chain deposition disease suggests it is a plasma cell disease: a case report

open access: yesJournal of International Medical Research, 2022
Heavy chain deposition disease (HCDD) is characterized by the deposition of truncated monoclonal immunoglobulin heavy chains along glomerular basement membranes.
Qingqing Rao, Ricong Xu, Qijun Wan
doaj   +1 more source

Distribution of immunoglobulin heavy chains in diseased synovia. [PDF]

open access: yesJournal of Clinical Pathology, 1986
Synovium from 142 patients with 12 different arthropathies was examined for the distribution of alpha, delta, gamma, and mu immunoglobulin heavy chains. A high proportion of plasma cells in the superficial subintima in all diseases reacted for alpha heavy chains. Only in rheumatoid disease did the synovium contain more than 10% of plasma cells reacting
Freemont, AJ, Rutley, C.
openaire   +4 more sources

AL amyloidosis with non-amyloid forming monoclonal immunoglobulin deposition; a case mimicking AHL amyloidosis

open access: yesBMC Nephrology, 2018
Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe   +6 more
doaj   +1 more source

Light and heavy chain deposition disease with focal amyloid deposition diagnosed with mass spectrometry: a case report

open access: yesBMC Nephrology, 2023
Background Light and heavy chain deposition disease (LHCDD) is a rare condition characterised by the deposition of immunoglobulin components in the kidneys.
Yuki Shimamoto   +11 more
doaj   +1 more source

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