Results 11 to 20 of about 167,466 (331)
Characterization of immunoglobulin heavy chain knockout rats [PDF]
European Journal of Immunology, 2010 AbstractThe rat is a species frequently used in immunological studies but, until now, there were no models with introduced gene‐specific mutations. In a recent study, we described for the first time the generation of novel rat lines with targeted mutations using zinc‐finger nucleases.
S. Ménoret +9 more
semanticscholar +4 more sources
Heavy and light chains of a homogeneous immunoglobulin‐G [PDF]
FEBS Letters, 1969 Zuhayr L. Awdeh +2 more
openalex +5 more sources
Immunoglobulin heavy chains in medaka (Oryzias latipes) [PDF]
BMC Evolutionary Biology, 2011 Abstract Background Bony fish present an immunological system, which evolved independently from those of animals that migrated to land 400 million years ago. The publication of whole genome sequences and the availability of several cDNA libraries for medaka (Oryzias latipes) permitted us to perform a thorough analysis
Magadán-Mompó, S. (Susana) +2 more
openaire +9 more sources
Disseminated Intravascular Coagulation Associated with Large Deletion of Immunoglobulin Heavy Chain
Iranian Journal of Allergy, Asthma and Immunology, 2021 Although the majority of monogenic defects underlying primary immunodeficiency are microlesions, large lesions like large deletions are rare and constitute less than 10% of these patients.
Abbas Khalili +4 more
doaj +1 more source
Diagnostic Pathology, 2022 Background Mu heavy chain disease is a rare lymphoid neoplasm characterized by vacuolated bone marrow plasma cells and secretion of defective mu immunoglobulin heavy chains. The biological basis of mu heavy chain disease is poorly understood.
Vandana Baloda +9 more
doaj +1 more source
Monoclonal gammopathy of renal significance: Spectrum of diseases and approach to a case
Saudi Journal of Kidney Diseases and Transplantation, 2021 The occurrence of kidney diseases associated with a monoclonal gammopathy in the absence of symptomatic multiple myeloma is increasingly recognized. When the kidney is involved, the monoclonal etiology of these diseases results in clinical and laboratory
Rohit Tewari +5 more
doaj +1 more source
Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch. [PDF]
PLoS ONE, 2017 Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu.
Binyue Han +5 more
doaj +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2023 Heavy chain diseases are rare B-cell neoplasms consisting of the production of a monoclonal immunoglobulin composed of the only heavy chain without corresponding light chains.
Maria Laura Bisegna +5 more
doaj +1 more source
Immunoglobulin heavy-chain-associated amyloidosis. [PDF]
Proceedings of the National Academy of Sciences, 1990 Immunoglobulin- or multiple myeloma-associated amyloidosis has been distinguished by the tissue deposition of Congophilic, fibrillar protein consisting of light chains or light-chain fragments (AL amyloidosis). We now report the isolation and characterization of another form of immunoglobulin-associated amyloid obtained from a patient who had extensive
Alan Solomon +2 more
openaire +3 more sources
Immunoglobulin light chain amyloidosis: 2022 update on diagnosis, prognosis, and treatment
American journal of hematology/oncology, 2022 Immunoglobulin light chain amyloidosis is a clonal, nonproliferative plasma cell disorder in which fragments of immunoglobulin light or heavy chain are deposited in tissues.
M. Gertz
semanticscholar +1 more source