Results 151 to 160 of about 136,376 (331)

Stereotactic body radiotherapy plus cadonilimab (PD‐1/CTLA‐4 bispecific antibody) as third‐line or beyond therapy for refractory solid tumors: A phase 1b study

open access: yesCancer Communications, EarlyView.
Abstract Background Cadonilimab is a humanized immunoglobulin G1 bispecific antibody targeting programmed cell death protein 1 (PD‐1) and cytotoxic T‐lymphocyte‐associated antigen 4 (CTLA‐4). This study aimed to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) combined with cadonilimab in patients with advanced recurrent or ...
Yao Xiao   +7 more
wiley   +1 more source

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin   +5 more
wiley   +1 more source

Efficient Photocatalytic Degradation of Methylene Blue From Aqueous Solution Using Hybrid Biomass‐Derived Nanostructured Carbon‐TiO2 Photocatalyst

open access: yesChemistry – A European Journal, EarlyView.
A hybrid photocatalyst of biomass‐derived carbon nanospheres and TiO₂ has been developed from waste coffee leaves, achieving 99% MB dye degradation. The carbon reduces the bandgap, boosting UV photocatalysis, and the material shows excellent stability and recyclability, offering a sustainable, scalable solution for wastewater treatment.
Aman Sharma   +4 more
wiley   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius   +6 more
wiley   +1 more source

Rhamnolipid Self‐Aggregation in Water–Bioglycerol Mixtures: Byproduct Valorization for Sustainable Formulation Design

open access: yesChemPlusChem, EarlyView.
Bioglycerol, the primary byproduct of biodiesel production, has the potential to be valorized as a cosolvent in industrial formulations. Surface tension and self‐diffusion data reveal that rhamnolipid self‐aggregation in water is poorly affected by the addition of bioglycerol up to very high concentrations. These results demonstrate that biosurfactants
Rodolfo Esposito   +8 more
wiley   +1 more source

Pre‐oviposition development of the brown anole (Anolis sagrei)

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling   +9 more
wiley   +1 more source

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