Results 41 to 50 of about 280,511 (396)

A comprehensive analysis of immunoglobulin heavy chain genes in the Bactrian camel (Camelus bactrianus) [PDF]

Frontiers of Agricultural Science and Engineering, 2015
Heavy chain only antibodies (HCAbs) represent a rare type of antibody that is devoid of light chains and the CH1 domain that have been reported in cartilaginous fish and camelids.
Zuoxiang LIANG,Tao WANG,Yi SUN,Wenlong YANG,Zhihong LIU,Jing FEI,Ying GUO,Qingwei MA,Qingjie PAN,Liming REN
doaj   +1 more source

Chromosomal location of the genes for human immunoglobulin heavy chains.

Proceedings of the National Academy of Sciences of the United States of America, 1979
We have studied somatic cell hybrids between P3x63Ag8 mouse myeloma cells deficient in hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) and either human peripheral lymphocytes or human lymphoblastoid or myeloma cells for the production of human ...
C. Croce, M. Shander, J. Martinis, L. Cicurel, G. D’Ancona, T. W. Dolby, H. Koprowski   +6 more
semanticscholar   +1 more source

Chimerization of antibodies by isolation of rearranged genomic variable regions by the polymerase chain reaction [PDF]

, 1991
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerization ofAbs.
Kaluzab, Brigitte, Schwirzke, Marina, Weidle, Ulrich H., Weiss, Elisabeth H., Weissenhorn, Winfried   +4 more
core   +1 more source

Diversity of immunoglobulin light chain genes in non-teleost ray-finned fish uncovers IgL subdivision into five ancient isotypes [PDF]

, 2018
The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish.
Andreyushkova, Daria A, Baranov, Konstantin O, Chikaev, Nikolai A, Gessner, Jörn, Guselnikov, Sergey V, Kulemzin, Sergey V, Makunin, Alexey I, Mechetina, Ludmila V, Najakshin, Alexander M, Schartl, Manfred, Stöck, Matthias, Taranin, Alexander V, Trifonov, Vladimir A, Warren, Wesley C, Wuertz, Sven   +14 more
core   +5 more sources

B cell receptor accessory molecule CD79α : characterisation and expression analysis in a cartilaginous fish, the spiny dogfish (Squalus acanthias) [PDF]

, 2013
Copyright © 2013.
Anderson, Bhargava, Bird, Bodine, Browne, Cambier, Campanella, Campbell, Campbell, Christopher J. Secombes, DeFranco, Dooley, Dooley, Dylke, Eason, Eckner, Engels, Fitzsimmons, Flajnik, Flajnik, Guselnikov, Ha, Hagman, Haire, Haman, Hardy, Heinemeyer, Helen Dooley, Hinds, Ito, Jang, Johnson, Jun Zou, Kabak, Kahsay, Kashiwamura, Larkin, Lee, Li, Luisiri, Lukin, Malecek, Mason, Minegishi, Miracle, Mount, Neuberger, Patterson, Petersen, Pfaffl, Pryjma, Rast, Ravi, Reddick, Reth, Reth, Reth, Roessler, Ronggai Li, Rumfelt, Sahoo, Sakaguchi, Salim, Sanchez, Sigrist, Sigvardsson, Smith, Steinke, Steve Bird, Tamura, Tiehui Wang, Travis, Volff, Walsh, Wang, Williams, Youn, Youn, Yu   +78 more
core   +2 more sources

Two Cases of Heavy Chain MGUS

Case Reports in Oncological Medicine, 2016
Heavy chain diseases are rare variants of B-cell lymphomas that produce one of three classes of immunoglobulin heavy chains, without corresponding light chains. We describe two patients with asymptomatic heavy chain monoclonal gammopathy.
Jan Van Keer, Björn Meijers, Michel Delforge, Gregor Verhoef, Koen Poesen   +4 more
doaj   +1 more source

Expressions of immunoglobulin M and immunoglobulin D heavy chain in B-chronic lymphocytic leukemia and their correlation with CD38 expression

Iraqi Journal of Hematology, 2017
Background: B-chronic lymphocytic leukemia (CLL) is a monoclonal malignancy characterized by an accumulation of small mature-looking B lymphocytes in the blood, bone marrow, and other tissues.
Ghid Nahd Abdul Muhssen, Hind Shaker AL-Mamoori, Majid Hameed Ahmed   +2 more
doaj   +1 more source

Allotypically related sequences in the Fd fragment of rabbit immunoglobulin heavy chains.

Biochemical Journal, 1971
The sequence has been completed of the N-terminal 94 residues of the variable section of the Fd fragment of heavy chains from rabbit immunoglobulin G (IgG) of allotype As1.
L. Mole, S. A. Jackson, R. Porter, J. Wilkinson   +3 more
semanticscholar   +1 more source

Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus. [PDF]

PLoS ONE, 2014
Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative ...
Jenni Liljavirta, Mikael Niku, Tiina Pessa-Morikawa, Anna Ekman, Antti Iivanainen   +4 more
doaj   +1 more source

Diagnosing a Challenging Case of Primary Amyloidosis using Capillary Electrophoresis [PDF]

National Journal of Laboratory Medicine, 2021
Amyloid Light chain (AL) amyloidosis is characterised by deposition of intact free light chains or their fragments in extracellular space. Here, authors describe the journey of a diagnostically challenging patient who presented with features of ...
rashmi verma, rajni saijpaul, Surbhi Garg, niharika jain, Vineeta V Batra   +4 more
doaj   +1 more source