Results 181 to 190 of about 478,815 (317)

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

Glia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis, Breana C. Dogan, Amy L. Stanek, Elliot B. Evans, Madelyn G. Coble, Hayli E. Spence‐Osorio, Karen L. G. Farizatto, Angie L. Mordant, C. Allie Mills, Laura E. Herring, Katherine T. Baldwin   +10 more
wiley   +1 more source

Vaginal microbiome dysbiosis and sexually transmitted infections correlate with concentrations of immunoglobulin isotypes in human cervicovaginal mucus: insights into HIV-1 transmission. [PDF]

Front Immunol
Akiso MM, Abook I, Mureithi MW, Kombo J, Koi P, Musando J, Chirchir RJ, McRaven MD, Carias AM, Joseph S, Anzala O, Hope TJ.   +11 more
europepmc   +1 more source

A Synthetic β‐Mannan Epitope Enables Immunization and Detection of Candida auris

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A synthetic β‐mannan epitope enables both active and passive immunization against Candida auris. Conjugation to the carrier protein CRM197 induces protective antibody responses, while monoclonal antibodies targeting the same epitope support detection using a lateral flow assay, linking glycochemistry with antifungal prevention and diagnostics ...
Emelie E. Reuber, Arnab Pradhan, Ian Leaves, Rajat K. Singh, Emer Hickey, Carola Geiler, Neil A. R. Gow, Alistair J. P. Brown, Peter H. Seeberger   +8 more
wiley   +2 more sources

Comprehensive Immune Repertoires of T Cell Receptor and B Cell Receptor Identify Key Immune Features Associated With Disease Activity of Systemic Lupus Erythematosus

MedComm, Volume 7, Issue 11, November 2026.
To characterize systemic immune features associated with disease activity, peripheral blood was collected from 32 active SLE patients, 30 stable SLE patients, and 35 healthy donors. Comprehensive immune profiling was performed using flow cytometry, immune repertoire sequencing, and bulk RNA sequencing.
Jingyi Wu, Zhuochao Zhou, Anrui Yu, Xia Lin, Yuyang Ren, Jialin Teng, Dehao Zhu, Fan Wang, Yijun You, Xiangjun Ji, Puyu Wang, Hongpu Li, Chengde Yang, Wenbo Wang, Yawei Du, Junna Ye   +15 more
wiley   +1 more source

Distribution of immunoglobulin isotypes and IgG subclasses in visceral leishmaniasis cases

, 2004
Visseral leishmaniasis erken tanısının zor olması, sağaltımda sıklıkla ilaç direnci ve relapslarla karşılaşılması nedeniyle, günümüzde halen sorun olmaya devam eden fatal, tropikal bir hastalıktır.
Tamer Şanlıdağ, Emin Limoncu, Özensoy Seray Töz, Sinem Akçalı, Yusuf Özbel, İ. Cüneyt Balcıoğlu   +5 more
core  

Double‐Antibody Sandwich Enzyme‐Linked Immunosorbent Assay for Detecting Feline Coronavirus Infection

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
In this study, a mouse monoclonal and rabbit polyclonal antibodies were used as capture and detection antibodies, respectively, to develop a DAS‐ELISA that can be used for viral antigen detection. ABSTRACT Objectives Double‐antibody sandwich enzyme‐linked immunosorbent assay (DAS‐ELISA) is a simple and accurate method for detecting viral pathogens ...
Bo Dong, Weijie Zou, Wenqian Hu, Hongxiao Wu, Yaqing Jing, Fuquan Xie, Shuo Zhang, Weiming Lin   +7 more
wiley   +1 more source

Signs of Cross‐Reactivity Between SARS‐CoV‐2 and Other Coronaviruses in a Pre‐Vaccine Swedish School Setting

Acta Paediatrica, Volume 115, Issue 11, Page 2616-2624, November 2026.
ABSTRACT Aim This pilot study explored signs of immunological cross‐reactivity between SARS‐CoV‐2 and human coronaviruses (HCoVs) in a Swedish school setting. Methods A cross‐sectional, hypothesis‐generating study was conducted late 2020 before vaccines against COVID‐19 were available.
Lina Schollin Ask, Sharon Kühlmann Berenzon, Ulrika Marking, Sara Nouiser, Andreas Bråve, Sören Andersson, Charlotta Nordenhäll, Tobias Alfvén, Teghesti Tecleab, Olof Hertting, Tyler Sandberg, Wanda Christ, Jonas Klingström, Kim Blom, Charlotta Nilsson   +14 more
wiley   +1 more source

Evidence for an early appearance of modern post‐switch immunoglobulin isotypes in mammalian evolution (II); cloning of IgE, IgG1 and IgG2 from a monotreme, the duck‐billed platypus, Ornithorhynchus anatinus

European Journal of Immunology, 2002
Molly Vernersson, Maria Aveskogh, Barry L. Munday, L. Hellman   +3 more
semanticscholar   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source