Results 1 to 10 of about 31,276 (113)

The Relevance of Anti-PF4 Antibody Isotypes and Endogenous Glycosaminoglycans and their Relationship with Inflammatory Biomarkers in Pulmonary Embolism Patients [PDF]

Clinical and Applied Thrombosis/Hemostasis, 2022
Introduction Previous studies have shown that inflammation may contribute to the interplay of endogenous glycosaminoglycans (GAGs) and anti-PF4 antibodies. In this study, we quantified the levels of anti-PF4 antibody isotypes and endogenous GAGs together
Bulent Kantarcioglu MD, Amir Darki MD, MSc, Fakiha Siddiqui BDS, Debra Hoppensteadt PhD, Joseph Lewis BA, Roland Krämer PhD, Cafer Adiguzel MD, Jawed Fareed PhD   +7 more
doaj   +2 more sources

Different antibody isotypes against tuberculosis: what we know and what we need to know [PDF]

Frontiers in Immunology
Humoral Immunity plays an important role during Mycobacterium tuberculosis(Mtb) infection. In mouse models, polyvalent and monoclonal antibodies targeting Mtb provided some protection against tuberculosis (TB). The five human antibody isotypes (IgG, IgM,
Huoming Li, Hao Li
doaj   +2 more sources

Fabrication of Microarrays for the Analysis of Serological Antibody Isotypes against Food Antigens [PDF]

Sensors, 2019
Food intolerance is delayed adverse food reactions which follow consumption of specific foods. The underlying mechanisms are not well understood, but food intolerance is often considered as a type 2 hypersensitivity reaction mediated by immunoglobulin G (
Jeahee Ryu, Soyoun Kim, Jaeseung Song, Daeun Kim, Narae Keum, Wonhee Jang, Hyosang Bae, Youngeun Kwon   +7 more
doaj   +2 more sources

Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses. [PDF]

PLoS Pathogens, 2016
Emerging data support a role for antibody Fc-mediated antiviral activity in vaccine efficacy and in the control of HIV-1 replication by broadly neutralizing antibodies.
Matthew Zirui Tay, Pinghuang Liu, LaTonya D Williams, Michael D McRaven, Sheetal Sawant, Thaddeus C Gurley, Thomas T Xu, S Moses Dennison, Hua-Xin Liao, Agnès-Laurence Chenine, S Munir Alam, M Anthony Moody, Thomas J Hope, Barton F Haynes, Georgia D Tomaras   +14 more
doaj   +2 more sources

Analysing Antibodies Against Respiratory Viruses in Breast Milk: A Pilot Study [PDF]

Viruses
Background: Lower respiratory tract infections remain a major cause of morbidity and mortality in infants worldwide. Newborns possess an immature immune system but acquire passive immunity through maternal antibodies transferred via the placenta (IgG ...
Sindre H. Hauan, Camilla H. Nundal, Sarah Lartey Jalloh, June Skudal, Elin Ekornes Håskjold, Sigrid Christiansen Bøe, Camilla Tøndel, Linn Marie Sørbye, Rebecca J. Cox, Karl A. Brokstad   +9 more
doaj   +2 more sources

A new multiplex SARS-CoV-2 antigen microarray showed correlation of IgG, IgA, and IgM antibodies from patients with COVID-19 disease severity and maintenance of relative IgA and IgM antigen binding over time.

PLoS ONE, 2023
Zoonotic spillover of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans in December 2019 caused the coronavirus disease 2019 (COVID-19) pandemic.
Marie Le Berre, Terézia Paulovčáková, Carolina De Marco Verissimo, Seán Doyle, John P Dalton, Claire Masterson, Eduardo Ribes Martínez, Laura Walsh, Conor Gormley, John G Laffey, Bairbre McNicholas, Andrew J Simpkin, Michelle Kilcoyne   +12 more
doaj   +2 more sources

Antibody Isotypes for Tumor Immunotherapy [PDF]

Transfusion Medicine and Hemotherapy, 2017
Thomas Valerius, Anna Duenkel, Ralf Schwanbeck   +2 more
exaly   +2 more sources

Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor

Antibodies, 2023
We have previously produced a toolkit of antibodies, comprising recombinant human antibodies of all but one of the human isotypes, directed against the polcalcin family antigen Phl p 7.
Susan K. Vester, Anna M. Davies, Rebecca L. Beavil, Balraj S. Sandhar, Andrew J. Beavil, Hannah J. Gould, Brian J. Sutton, James M. McDonnell   +7 more
doaj   +1 more source

Framework for Characterizing Longitudinal Antibody Response in Children After Plasmodium falciparum Infection

Frontiers in Immunology, 2021
Human Plasmodium infection produces a robust adaptive immune response. Time courses for 104 children followed for 42 days after initiation of Plasmodium falciparum chemotherapy were assayed for antibody levels to the five isotypes of human ...
Eric Rogier, Doug Nace, Pedro R. Dimbu, Brian Wakeman, Jan Pohl, James G. Beeson, James G. Beeson, James G. Beeson, Chris Drakeley, Kevin Tetteh, Mateusz Plucinski, Mateusz Plucinski   +11 more
doaj   +1 more source

The synergistic effects of the constant region and variable heavy chain families of multimeric immunoglobulin M on its interaction with Fc-mu receptor and antigen

Exploration of Immunology, 2022
Aim: As the primary response antibody with increasing use as a therapeutic immunoglobulin (Ig) format, IgM is also the largest antibody structure among the five major human isotypes. Spontaneously formed pentamers and hexamers of IgM have avidity effects
Wei-Li Ling, Samuel Ken-En Gan
doaj   +1 more source