Results 31 to 40 of about 583,416 (296)

Variation in baseline antibody levels across CC strains and antibody isotypes.

, 2022
Total serum antibody levels for (A) IgM, (B) IgA, (C) total IgG, (D) IgG1, (E) IgG2a, (F) IgG2b, (G) IgG2c, and (H) IgG3 were quantified by ELISAs. Each plot is individually ordered so that the strain with the greatest strain mean is at the top of the ...
Alan C. Whitmore (14305284), Emily A. Madden (12890646), Ginger D. Shaw (12508627), Fernando Pardo-Manuel de Villena (10053162), James G. Xenakis (12867292), Kenneth S. Plante (10195928), Colton L. Linnertz (6443620), Martin T. Ferris (10001111), Mark T. Heise (10053165), Pablo Hock (14305293), Timothy A. Bell (7249760), Brea K. Hampton (14305281), Breantie Parotti (14305290), Kelsey E. Noll (14305287), Samuel P. Boyson (9546459)   +14 more
core   +1 more source

IgM specific to lipopolysaccharide of Vibrio cholerae is a surrogate antibody isotype responsible for serum vibriocidal activity.

PLoS ONE, 2019
Serum vibriocidal antibody assays have long been used to evaluate the immunogenicity of cholera vaccines formulated with killed whole-cell Vibrio cholerae.
Jae Seung Yang, So Jung An, Mi Seon Jang, Manki Song, Seung Hyun Han   +4 more
doaj   +1 more source

Murine antibody isotypes and CDR sequence comparisons.

, 2018
Murine antibody isotypes and CDR sequence comparisons.
Fiona E. Scott (5566007), A. Munro Neville (354616), Benjamin Gloria (5566001), Andrew M. Scott (172529), Hong Li (20183), Manuel Zeitelhofer (150938), Bruno Catimel (2177790), Angelo Perani (5566004), Laura Allan (3765208), Ingrid Nilsson (157323), Xicong Liu (5565998), Carmel Murone (665264), Ulf Eriksson (157345)   +12 more
core   +1 more source

Human Immunoglobulin G Cannot Inhibit Fibrinogen Binding by the Genetically Diverse A Domain of Staphylococcus aureus Fibronectin-Binding Protein A

mSphere, 2018
The fibronectin-binding protein A (FnBPA) is a cell surface-associated protein of Staphylococcus aureus which mediates adherence to the host extracellular matrix and is important for bacterial virulence.
P. Martijn den Reijer, Mehri Tavakol, Nicole Lemmens-den Toom, Dikra Allouch, Sheila Thomas, Vannakambadi K. Ganesh, Ya-Ping Ko, Henri A. Verbrugh, Willem J. B. van Wamel   +8 more
doaj   +1 more source

Why antibody isotype matters for immunotherapy. [PDF]

Antib Ther
Abstract Monoclonal antibodies (mAbs), engineered to recognize disease-associated antigens, are central to cancer immunotherapy due to their ability to block or eliminate malignant cells by engaging immune effector mechanisms. Yet many tumors evade or suppress these responses, and many patients fail to achieve durable clinical benefit,
Kleinau S.
europepmc   +2 more sources

Lower levels of IgG1 in comparison with IgG2a are associated with protective immunity against Leishmania tropica infection in BALB/c mice

Journal of Microbiology, Immunology and Infection, 2017
Leishmania (L.) tropica is the causative agent of different forms of human leishmaniasis. There is little information about the role of Leishmania-specific antibodies in the immune response against L. tropica infection.
Mosayeb Rostamian, Saeed Sohrabi, Hanie Kavosifard, Hamid M. Niknam   +3 more
doaj   +1 more source

Higher mucosal antibody concentrations in women with genital tract inflammation

Scientific Reports, 2021
Inflammatory cytokines augment humoral responses by stimulating antibody production and inducing class-switching. In women, genital inflammation (GI) significantly modifies HIV risk. However, the impact of GI on mucosal antibodies remains undefined.
Parveen Sobia, Thevani Pillay, Lenine J. P. Liebenberg, Aida Sivro, Leila E. Mansoor, Farzana Osman, Jo-Ann S. Passmore, Quarraisha Abdool Karim, Salim S. Abdool Karim, Cheryl Baxter, Lyle R. McKinnon, Derseree Archary   +11 more
doaj   +1 more source

Localization of the selected peptides within the constant region of different antibody isotypes.

, 2013
Localization of the selected peptides within the constant region of different antibody isotypes.
Pier Paolo Zanello (328939), Alberto Spisni (328945), Serena Galati (328941), Elena Gabrielli (290619), Thelma A. Pertinhez (328944), Tiziana D'Adda (328940), Denise C. Arruda (320174), Stefania Conti (92354), Walter Magliani (92353), Eva Pericolini (290617), Marcia R. Pinto (328943), Luiz R. Travassos (92355), Anna Vecchiarelli (290625), Silvia Arancia (328942), Flavia De Bernardis (264590), Luciano Polonelli (92344), Tecla Ciociola (309997)   +16 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Antibodies and their receptors: different potential roles in mucosal defence

Frontiers in Immunology, 2013
Over recent years it has become increasingly apparent that mucosal antibodies are not only restricted to the IgM and IgA isotypes, but that also other isotypes and particularly IgG can be found in significant quantities at some mucosal surfaces, such as ...
Rachel eHorton, Gestur eVidarsson
doaj   +1 more source