Results 211 to 220 of about 20,447 (254)
Immunoglobulin Isotypes in Human Minor Gland Saliva
Lower labial, upper labial, palatine (minor), and parotid (major) gland saliva samples from 18 young adult males were quantitatively assayed for the presence of IgAl, IgA2, IgM, and IgG. The mean (± standard deviation) concentrations of IgA (sum of IgAl + IgA2) were 79 ± 42 μg/mL (parotid), 111 ± 42 μg/mL (lower labial), 69 ± 72 μg/mL (upper labial ...
D J, Smith, M A, Taubman, P, Ali-Salaam
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Immunoglobulin light chain isotypes in the teleost Trematomus bernacchii
Molecular Immunology, 2008Three immunoglobulin light chain (IgL) isotypes TrbeL1, TrbeL2, and TrbeL3 were identified in the Antarctic teleost Trematomus bernacchii by immunoscreening a cDNA expression library, and using RT-PCR, and 5' RACE. One of them was distinguished in two subisotypes TrbeL1A and TrbeL1B.
Maria Rosaria Coscia +2 more
exaly +4 more sources
Immunoglobulin isotypes in childhood asthma
The Indian Journal of Pediatrics, 1999Immunoglobulin isotypes (IgG, IgA, IgM, IgD, IgE) in serum were investigated in 64 Libyan children with mild to moderately severe asthma (age: 1-12 years; sex: 39 males, 25 females) (Group A) and in 57 healthy Libyan children (age: 1-12 years; sex: 30 males, 27 females (Group B).
F I, Najam +2 more
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Monoclonal Antibodies to Murine Immunoglobulin Isotypes
Hybridoma, 1983We have obtained cell lines producing monoclonal antibodies against mu, alpha, lambda, and lambda 1 by fusing the mouse myeloma P3X63Ag8.653 with spleen cells from Lewis rats immunized with several lambda 1 bearing myeloma proteins. The anti-lambda 1 antibody is particularly useful.
S, Weiss, K, Lehmann, M, Cohn
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Immunoglobulin Isotype Expression
1978Many different kinds of observations suggest that during development of the B cell line, individual V H genes determining the antibody specificity of an immunoglobulin molecule can be expressed with multiple C H genes. Thus each clone of B cells, defined by expression of a variable-region gene for the light and heavy chains of the immunoglobulin ...
J F, Kearney, E R, Abney
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Allotypic and isotypic aspects of human immunoglobulin A
Molecular Immunology, 1983The location of isotypic, isoallotypic and allotypic determinants is reviewed in the light of data obtained when specific antisera are tested with proteolytic fragments of IgA molecules or mutants of IgA obtained from patients with alpha-heavy chain disease. Isotypic determinants are distributed throughout the alpha chain constant regions although when
E, van Loghem, J, Biewenga
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Immunoglobulin isotype switching in xid mice
Molecular Immunology, 1995Mice with the x-linked immunodeficiency mutation (xid) are unresponsive to polysaccharide antigens, lack a subset of B cells, and have low serum IgM (2-20% of normal) and IgG3 (3% of normal). Because of the disproportionate reduction of IgG3, the ability of B cells from xid mice to switch to gamma 3 was examined.
K A, Brorson +2 more
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Immunoglobulin Isotypes: Structure, Function, and Genetics
2000Immunoglobulin (Ig) classes (in mammals, IgM, IgA, IgD, IgG, IgE) are defined by the isotypes of heavy (H) chains (µ, α, δ, γ, and e). Each isotype is in turn distinguished by unique structures in its constant region domains. These different structures confer distinctive functions on the Ig classes.
E, Bengtén +5 more
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The Isotypic Circuit: Immunoglobulins, Fc Receptors and Immunoglobulin Binding Factors
International Reviews of Immunology, 1987(1987). The Isotypic Circuit: Immunoglobulins, Fc Receptors and Immunoglobulin Binding Factors. International Reviews of Immunology: Vol. 2, No. 2, pp. 221-240.
W H, Fridman +5 more
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Mechanism and Regulation of Immunoglobulin Isotype Switching
1993Publisher Summary This chapter focuses on the molecular mechanisms of switch recombination and other possible modes of isotype switching. It discusses the regulation of isotype switching, especially by T cells and the cytokines they produce. Virtually all of the analyses of the mechanisms and regulation of switching are done in either mouse or human,
R L, Coffman, D A, Lebman, P, Rothman
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