Failed Mucosal Allostasis Distinguishes Murine IgG‐ From IgE‐Mediated Recurrent Severe Anaphylaxis
This study investigates IgE‐ and IgG‐mediated pathways in acute and recurrent anaphylaxis using a murine ASA‐PSA model, assessing barrier integrity, immune activation and tissue remodelling across pulmonary and intestinal compartments. Recurrent IgE‐ and IgG‐mediated anaphylaxis produces divergent mucosal outcomes despite comparable systemic severity ...
Abdurrahman Simsek +8 more
wiley +1 more source
Unraveling BCR Repertoire Diversity and its Impact on Glucocorticoid Therapy in Pediatric Idiopathic Nephrotic Syndrome. [PDF]
Luo Y +10 more
europepmc +1 more source
Multiplex Detection of Immunoglobulins Uncovers Intrathecal IgA Elevation in Multiple Sclerosis. [PDF]
Apeltsin L +6 more
europepmc +1 more source
ABSTRACT Interleukin (IL)‐10‐producing B cells represent an archetype for the regulatory functions of B cells. Here, we review the cell‐surface receptors and transcriptional regulators that control IL‐10 expression in B cells and enable their regulatory function in vivo.
Bui Thi Cuc +4 more
wiley +1 more source
Class switched bovine ultralong CDR H3 amplicons versus canonical in immune and non-immune tissues. [PDF]
Hissen KL +10 more
europepmc +1 more source
Abstract Concerns regarding the safety of bisphenol A (BPA) and the resulting restrictions on its use in food contact materials (FCM) have been broadened to other ‘bisphenols and bisphenol derivatives’ (BPs). Several of these substances are considered hazardous due to their classification as carcinogenic, mutagenic, toxic to reproduction (CMR) or ...
EFSA Panel on Food Contact Materials (FCM) +22 more
wiley +1 more source
Human primary antibody response to vaccination follows a partially sequential class-switching program with a checkpoint at IGHG2. [PDF]
Montamat-Garcia G +16 more
europepmc +1 more source
Prognostic value of antiphospholipid antibodies in pregnancy outcomes in systemic lupus erythematosus. [PDF]
Zhang X +12 more
europepmc +1 more source
Immunoglobulins in recurrent pregnancy loss: Emerging biomarkers and therapeutic targets. [PDF]
Kulsum U +8 more
europepmc +1 more source
Method qualification of an electrochemiluminescence assay to quantitate anti-FcεR1α autoantibodies: a case study of an antibody-based biomarker. [PDF]
Lawless MJ, Chan N, Patel K, Mudiyala S.
europepmc +1 more source

