Results 131 to 140 of about 29,558 (298)

Localized AL amyloidosis

open access: yesТерапевтический архив
Localized light chain (AL) amyloidosis (amyloidoma) is a rare disease with unclear pathogenesis and undeveloped approaches to therapy. This article presents 3 clinical observations of localized AL amyloidosis with lesions of the respiratory tract, eyes ...
Nelly A. Kashchavtseva   +4 more
doaj   +1 more source

A Mixed Frequency BVAR for the Australian Economy*

open access: yesEconomic Record, EarlyView.
A mixed frequency vector autoregression (MFVAR) model is proposed for nowcasting, forecasting and backcasting Australian macroeconomic indicators at monthly and quarterly frequencies. A novel augmented Minnesota prior for MFVAR models is also introduced.
Kelly Trinh, Jamie L. Cross
wiley   +1 more source

An unusual case of multiple myeloma [PDF]

open access: yes, 2013
The case concerns the unusual presentation of a non-secretory multiple myeloma with diarrhoea secondary to large bowel infiltration. In December 2009, a 74-year-old lady presented to hospital and complained of a two year history of intermittent ...
Delicata, Julian, Farrugia, Daniel
core  

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz   +17 more
wiley   +1 more source

Circulating tumour cells (CTCs) in haematological malignancies: Advances in biology and clinical relevance with a focus on multiple myeloma

open access: yesBritish Journal of Haematology, EarlyView.
Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu   +3 more
wiley   +1 more source

Free kappa light chains in cerebrospinal fluid as a biomarker to assess risk conversion to multiple sclerosis

open access: yesMultiple Sclerosis Journal - Experimental, Translational and Clinical, 2015
Background Multiple sclerosis (MS) initiates with a first attack or clinically isolated syndrome (CIS). The importance of an early treatment in MS leads to the search, as soon as possible, for novel biomarkers which can predict conversion from CIS to MS.
P Menéndez-Valladares   +8 more
doaj   +1 more source

Unusual Cutaneous and Lymphatic Findings in an Adult Patient

open access: yes
JEADV Clinical Practice, EarlyView.
Sarah Preis   +4 more
wiley   +1 more source

Renal dysfunction in symptomatic Waldenström macroglobulinaemia: A nationwide Italian multicentre study

open access: yesBritish Journal of Haematology, EarlyView.
Renal dysfunction represents a possible underrecognized complication of symptomatic WM; this condition correlates with adverse global and disease‐specific clinical outcomes. Summary The prognostic significance of impaired renal function in Waldenström macroglobulinaemia (WM) remains poorly defined.
Nicolò Danesin   +27 more
wiley   +1 more source

Stimulation of κ Light-Chain Gene Rearrangement by the Immunoglobulin, µ Heavy Chain in a Pre-B-Cell Line [PDF]

open access: yes, 1993
B-lymphocyte development exhibits a characteristic order of immunoglobulin gene rearrangements. Previous work has led to the hypothesis that expression of the immunoglobulin µ heavy chain induces rearrangement activity at the K light-chain locus.
Baltimore, David   +3 more
core  

Serum free light chain concentration and ratio‐based criterion for myeloma‐defining event, in its current version, is untenable

open access: yesBritish Journal of Haematology, EarlyView.
Summary Clinical decision‐making based on myeloma‐defining event criteria using thresholds for involved serum free light chain level of 10 mg/dL and ratio of involved to uninvolved light chain of >100 is a poor indicator for the risk of progression to multiple myeloma.
Gurmukh Singh
wiley   +1 more source

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