Results 91 to 100 of about 5,095,980 (121)

Hepatic amyloidosis with light chain deposition disease. A rare association.

open access: yes, 2000
Monoclonal immunoglobulin deposition diseases are due to pathological protein deposition in various tissues and organs. Protein deposits may be found in a single tissue or systemically and the organs most frequently involved are kidney, heart, peripheral
De Paoli A   +7 more
core   +1 more source

Refractory IgM AL amyloidosis with massive soft tissue tumors: Rescue with zanubrutinib. A case report

open access: yesCurrent Problems in Cancer: Case Reports
Waldenström macroglobulinemia (WM) is a rare indolent B-cell non-Hodgkin lymphoma with lymphoplasmacytic morphology, associated with immunoglobulin M (IgM) monoclonal gammopathy. The coexistence of WM and immunoglobulin light chain (AL) amyloidosis is an
Piotr Jachimowski   +5 more
doaj   +1 more source

Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2018

open access: yes, 2018
Immunoglobulin light chain amyloidosis (AL) should be considered in any patient that presents to a cancer care provider with nephrotic range proteinuria, heart failure with preserved ejection fraction, non-diabetic peripheral neuropathy, unexplained ...
Morie A. Gertz
core   +1 more source

Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL):A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis

open access: yes, 2005
We undertook this study to develop uniformly accepted criteria for the definition of organ involvement and response for patients on treatment protocols for immunoglobulin light-chain amyloidosis (AL).
Hazenberg, BP; id_orcid   +13 more
core   +1 more source

Systemic Light Chain Amyloidosis [PDF]

open access: yes
Systemic light chain (AL) amyloidosis is a rare protein misfolding and deposition disorder. Clonal plasma cells or rarely B cells produce immunoglobulin light chains with the potential to misfold.
Minnema, Monique   +4 more
core  

Immunoglobulin light chain amyloidosis

open access: yes, 2014
Primary light chain amyloidosis is the most common form of systemic amyloidosis and is caused by misfolded light chains that cause proteotoxicity and rapid decline of vital organ function.
Gertz MA   +4 more
core   +1 more source

Diagnosing Light Chain Amyloidosis on Temporal Artery Biopsies for Suspected Giant Cell Arteritis

open access: yes, 2017
Although still rarely diagnosed, amyloid light chain (AL) amyloidosis is the most common form of systemic amyloidosis. It is characterized by misfolded monoclonal immunoglobulin light chain fragments that accumulate extracellularly as amyloid fibrils ...
Rosanna A. M. Ghinai; Shameem Mahmood; Pinias Mukonoweshuro; Sally Webber; Ashutosh D. Wechalekar; Sally E. Moore
core  

A case of pulmonary transthyretin amyloidosis with concurrent mycobacterial tuberculosis infection

open access: yesRespirology Case Reports
Amyloidosis is a pathological deposition disease that causes a spectrum of organ dysfunction. Pulmonary involvement is generally associated with immunoglobulin light chain type (AL) amyloid. Transthyretin (ATTR) amyloid build up in the lung is thought to
Hanson Siu   +5 more
doaj   +1 more source

Treatment Options For Relapsed/refractory Systemic Light-Chain (AL) Amyloidosis: Current Perspectives

open access: yesJournal of Blood Medicine, 2019
Shayna Sarosiek, Vaishali Sanchorawala Amyloidosis Center, Boston University School of Medicine and Boston Medical Center, Boston, MA, USACorrespondence: Shayna Sarosiek; Vaishali SanchorawalaAmyloidosis Center, Boston University School of Medicine and ...
Sarosiek S, Sanchorawala V
doaj  

Nutritional status of outpatients with systemic immunoglobulin light-chain amyloidosis

open access: yes, 2006
Background: Maintenance of a good nutritional status is associated with prolonged survival in many chronic diseases. To date, the nutritional status of outpatients with immunoglobulin light-chain (AL) amyloidosis has not been evaluated.
Vagia Cristina   +7 more
core  

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