Results 101 to 110 of about 4,867,269 (191)

Refractory IgM AL amyloidosis with massive soft tissue tumors: Rescue with zanubrutinib. A case report

Current Problems in Cancer: Case Reports
Waldenström macroglobulinemia (WM) is a rare indolent B-cell non-Hodgkin lymphoma with lymphoplasmacytic morphology, associated with immunoglobulin M (IgM) monoclonal gammopathy. The coexistence of WM and immunoglobulin light chain (AL) amyloidosis is an
Piotr Jachimowski, Łukasz Ciulkiewicz, Mateusz Ziarkiewicz, Bogna Ziarkiewicz-Wróblewska, Marta Legatowicz-Koprowska, Krzysztof Jamroziak   +5 more
doaj   +1 more source

Concurrent Therapy for Immunoglobulin Light Chain Cardiac Amyloidosis and Transthyretin Cardiac Amyloidosis

Internal Medicine
Cardiac amyloidosis (CA), predominantly caused by amyloid transthyretin (ATTR) or immunoglobulin light chain (AL), has a poor prognosis, and a precise diagnosis is crucial because the optimal treatments differ between the two conditions. However, diagnosing AL-CA is challenging because of the unavailability of effective AL-detecting antibodies ...
Horigome, Yuichi, Ishii, Shunsuke, Matsumoto, Manabu, Ikeda, Yoshihiko, Hatakeyama, Kinta, Ako, Junya, Suzuki, Takahiro   +6 more
openaire   +3 more sources

Hepatic amyloidosis with light chain deposition disease. A rare association.

, 2000
Monoclonal immunoglobulin deposition diseases are due to pathological protein deposition in various tissues and organs. Protein deposits may be found in a single tissue or systemically and the organs most frequently involved are kidney, heart, peripheral
De Paoli A, Lavazza MT, Gualdoni G, Beretta R., Casiraghi MA, Assi A, PALLADINI, GIOVANNI, Beretta A   +7 more
core   +1 more source

C-myc and immunoglobulin kappa light chain constant genes are on the 8q+ chromosome of three Burkitt lymphoma lines with t(2;8) translocations [PDF]

, 1984
We have determined the localization of c-myc and the immunoglobulin kappa light chain genes on the 8q+/2p- chromosomes of the three Burkitt lymphoma lines BL21, LY66 and LY91 with t(2;8) translocation by in situ hybridization.
Cremer, Thomas, Lenoire, Gilbert M., Rappold, Gudrun A., Bornkamm, Georg W., Adolph, Sabine, Hameister, Horst, Henglein, Berthold, Freese, Ulrich-K.   +7 more
core   +1 more source

A case of pulmonary transthyretin amyloidosis with concurrent mycobacterial tuberculosis infection

Respirology Case Reports
Amyloidosis is a pathological deposition disease that causes a spectrum of organ dysfunction. Pulmonary involvement is generally associated with immunoglobulin light chain type (AL) amyloid. Transthyretin (ATTR) amyloid build up in the lung is thought to
Hanson Siu, Ari Mond, James Shaw, Ruth Chin, Patrick Hosking, Hari Wimaleswaran   +5 more
doaj   +1 more source

Treatment of Immunoglobulin Light Chain Amyloidosis [PDF]

Mayo Clinic Proceedings, 2015
Angela Dispenzieri, Francis Buadi, Shaji K. Kumar, Craig B. Reeder, Tamur Sher, Martha Q. Lacy, Robert A. Kyle, Joseph R. Mikhael, Vivek Roy, Nelson Leung, Martha Grogan, Prashant Kapoor, John A. Lust, David Dingli, Ronald S. Go, Yi Lisa Hwa, Suzanne R. Hayman, Rafael Fonseca, Sikander Ailawadhi, P. Leif Bergsagel, Ascher Chanan-Khan, S. Vincent Rajkumar, Stephen J. Russell, Keith Stewart, Steven R. Zeldenrust, Morie A. Gertz   +25 more
openaire   +1 more source

Safety and efficacy of teclistamab in systemic immunoglobulin light chain amyloidosis. [PDF]

Blood Cancer J, 2023
Chakraborty R, Bhutani D, Maurer MS, Mohan M, Lentzsch S, D'Souza A.   +5 more
europepmc   +1 more source

Systemic Light Chain Amyloidosis [PDF]

Systemic light chain (AL) amyloidosis is a rare protein misfolding and deposition disorder. Clonal plasma cells or rarely B cells produce immunoglobulin light chains with the potential to misfold.
Minnema, Monique, Schönland, Stefan
core  

Diagnosing Light Chain Amyloidosis on Temporal Artery Biopsies for Suspected Giant Cell Arteritis

, 2017
Although still rarely diagnosed, amyloid light chain (AL) amyloidosis is the most common form of systemic amyloidosis. It is characterized by misfolded monoclonal immunoglobulin light chain fragments that accumulate extracellularly as amyloid fibrils ...
Rosanna A. M. Ghinai; Shameem Mahmood; Pinias Mukonoweshuro; Sally Webber; Ashutosh D. Wechalekar; Sally E. Moore
core  

Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis ARTICLE

, 2020
P atients with immunoglobulin light chain amyloidosis are at risk for both thrombotic and bleeding complications. While the hemostatic defects have been extensively studied, less is known about thrombotic complications in this disease. This retrospective
Fangui Sun, Luke I Masha, J Mark Sloan, Vaishali Sanchorawala, John L Berk, Andrea Havasi, Katherine M Bever, Lauren Stern, David C Seldin   +8 more
core